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Review
. 2023 Sep;57(5):192-203.
doi: 10.5152/j.aott.2023.23074.

Venous thromboembolism in orthopedic surgery: Global guidelines

Kadir Uzel  1 , İbrahim Azboy  1 , Javad Parvizi  2
Affiliations
Review

Venous thromboembolism in orthopedic surgery: Global guidelines

Kadir Uzel et al. Acta Orthop Traumatol Turc. 2023 Sep.

Abstract

Venous thromboembolism (VTE) is a severe complication that can occur after major orthopedic procedures. As VTE-related morbidity and mortality are a significant concern for both medical professionals and patients, and preventative measures are typically employed. Multiple organizations, including the American College of Chest Physicians (ACCP) and the American Academy of Orthopedic Surgeons (AAOS), have developed guidelines for VTE prophylaxis specifically in patients undergoing joint replacement procedures. However, recently, the International Consensus Meeting (ICM) was convened, which brought together over 600 experts from 68 countries and 135 international societies. These experts, spanning a range of medical disciplines including orthopedic surgery, anesthesia, cardiology, hematology, vascular, and internal medicine, conducted a comprehensive review of the literature using a strict Delphi process to generate practical recommendations for VTE prophylaxis across all types of orthopedic procedures. This review article summarizes some of the recommendations of the ICM.

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References

    1. Søgaard KK, Schmidt M, Pedersen L, Horváth-Puhó E, Sørensen HT. 30-year mortality after venous thromboembolism: a population-based cohort study. Circulation. 2014;130(10):829 836. (10.1161/CIRCULATIONAHA.114.009107) - DOI - PubMed
    1. Falck-Ytter Y, Francis CW, Johanson NA, et al. Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2):278 325. - PMC - PubMed
    1. Jacobs JJ, Mont MA, Bozic KJ, et al. American Academy of Orthopaedic Surgeons clinical practice guideline on preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty. J Bone Joint Surg Am. 2012;94(8):746 747. (10.2106/JBJS.9408.ebo746) - DOI - PMC - PubMed
    1. Groff H, Azboy I, Parvizi J. Differences in reported outcomes in industry-funded vs nonfunded studies assessing thromboprophylaxis after total joint arthroplasty. J Arthroplasty. 2018;33(11):3398 3401. (10.1016/j.arth.2018.06.025) - DOI - PubMed
    1. Chan NC, Siegal D, Lauw MN, et al. A systematic review of contemporary trials of anticoagulants in orthopaedic thromboprophylaxis: suggestions for a radical reappraisal. J Thromb Thrombolysis. 2015;40(2):231 239. (10.1007/s11239-014-1153-7) - DOI - PubMed

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