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. 2023 Oct;51(10):3000605231202350.
doi: 10.1177/03000605231202350.

Obstructive jaundice treatment during the COVID-19 pandemic: retrospective cohort study at a single tertiary care center in Serbia

Borislav Toskovic  1   2 , Batric Vukcevic  3 , Darko Zdravkovic  1   2 , Bogdan Crnokrak  1   2 , Igor Nadj  1 , Ana Sekulic  1   2 , Davor Mrda  1 , Slobodan Todorovic  1   2 , Ranko Lazovic  3   4 , Vladimir Milosavljevic  1
Affiliations

Obstructive jaundice treatment during the COVID-19 pandemic: retrospective cohort study at a single tertiary care center in Serbia

Borislav Toskovic et al. J Int Med Res. 2023 Oct.

Abstract

Objective: We aimed to compare mortality and complication rates in patients treated for obstructive jaundice before and during the COVID-19 pandemic in a tertiary care center in Serbia.

Methods: We conducted a retrospective cohort study among a first group of patients treated between 1 January 2017 and 1 January 2019. The second group was treated between 1 March 2020 and 1 March 2022.

Results: The first group comprised 35 patients, and the second group (in which all patients were SARS-CoV-2 positive) included 18 patients; 37 and 16 patients were treated for malignant and benign diseases, respectively. The groups did not differ significantly regarding the diagnoses and treatment received. The second group showed significantly higher aspartate aminotransferase levels and lower white blood cell, C-reactive protein, and interleukin 6 levels. Mortality and complication rates did not differ significantly between groups. All deceased patients in the second group had significant radiologic findings associated with COVID-19 pneumonia.

Conclusions: COVID-19 infection is a risk factor in treating obstructive jaundice. This study illustrates the potential influence of COVID-19 on mortality after obstructive jaundice treatment. COVID-19 pneumonia may be a significant risk factor for mortality in patients treated for obstructive jaundice.

Keywords: COVID-19 pandemic; mortality; obstructive jaundice; retrospective study; risk factor; surgery.

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Conflict of interest statement

Declaration of conflicting interestThe authors declare that there is no conflict of interest.

References

    1. Manzia TM, Angelico R, Parente A, et al. Global management of a common, underrated surgical task during the COVID-19 pandemic: Gallstone disease - An international survery. Ann Med Surg (Lond) 2020; 57: 95–102. - PMC - PubMed
    1. Cai M, Wang G, Zhang L, et al. Performing abdominal surgery during the COVID-19 epidemic in Wuhan, China: a single-centered, retrospective, observational study. Br J Surg 2020; 107: e183–e185. - PMC - PubMed
    1. Sandblom G, Österberg J, Rogmark P, et al. Impact of the COVID-19 pandemic on the management of gallstone surgery: A Swedish population-based study. Scand J Surg 2022; 111: 14574969211070389. - PubMed
    1. COVIDSurg Collaborative. Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA: A Prospective Multicenter Study. Ann Surg 2022; 275: 247–251. - PMC - PubMed
    1. COVIDSurg Collaborative. Global guidance for surgical care during the COVID-19 pandemic. Br J Surg 2020; 107: 1097–1103. - PMC - PubMed