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Review
. 2024 Jun;45(6):403-410.
doi: 10.1055/a-2191-0518. Epub 2023 Oct 12.

Practical Aspects of Cardiopulmonary Exercise Testing in Children

Affiliations
Review

Practical Aspects of Cardiopulmonary Exercise Testing in Children

Tim Takken et al. Int J Sports Med. 2024 Jun.

Abstract

The use of cardiopulmonary exercise testing (CPET) in pediatrics provides critical insights into potential physiological causes of unexplained exercise-related complaints or symptoms, as well as specific pathophysiological patterns based on physiological responses or abnormalities. Furthermore, CPET helps evaluate exercise performance in children with chronic (lung/heart) diseases. For instance, it can ascertain any adverse reaction to exercise and estimate the effects of specific treatment measures. It affords a global assessment of the pathophysiological patterns, responses and abnormalities to exercise that is inadequately reflected by resting lung function and/or cardiac function assessment. Clinical interpretation of the results of a CPET in pediatrics requires specific knowledge regarding pathophysiological responses and interpretative strategies that can be adapted to address concerns specific to the child's medical condition or disability.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
The VO 2peak and VO 2peak per kilogram body mass in relation to height for boys and girls. Data reanalyzed after with permission.
Fig. 2
Fig. 2
Flowchart for the selection of CPET reference values.
Fig. 3
Fig. 3
Example of a Wasserman 9-panel plot (2012 edition 30 ) for a healthy girl. For explanations and abbreviations, see text.

References

    1. Ross R, Blair S N, Arena R et al.Importance of assessing cardiorespiratory fitness in clinical practice: A case for fitness as a clinical vital sign: A scientific statement from the american heart association. Circulation. 2016;134:e653–e699. - PubMed
    1. Raghuveer G, Hartz J, Lubans D R et al.Cardiorespiratory fitness in youth: an important marker of health: A scientific statement from the american heart association. Circulation. 2020;142:e101–e118. - PMC - PubMed
    1. Bongers B C, Hulzebos H J, van Brussel M . the Netherlands: Uitgeverij BOXPress; 2014. Pediatric norms for cardiopulmonary exercise testing. 2nd edition. ‘s-Hertogenbosch.
    1. Müller J, Hager A, Diller G-P et al.Peak oxygen uptake, ventilatory efficiency and QRS-duration predict event free survival in patients late after surgical repair of tetralogy of Fallot. Int J Cardiol. 2015;196:158–164. - PubMed
    1. Duppen N, Takken T, Hopman M T et al.Systematic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol. 2013;168:1779–1787. - PubMed