Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Oct 6;18(12):4400-4403.
doi: 10.1016/j.radcr.2023.09.037. eCollection 2023 Dec.

A rare case of duodenal adenocarcinoma

Affiliations
Case Reports

A rare case of duodenal adenocarcinoma

Ho Xuan Tuan et al. Radiol Case Rep. .

Abstract

Duodenal adenocarcinoma is very rare. Its clinical picture is nonspecific and the diagnosis is often accidental. The factors that affect survival are difficult to determine because the number of patients is not high. The common site of duodenal tumors and surgical removal are also debatable. The treatment guidelines published so far have mostly been evaluated in retrospective studies conducted over a 20-year period with relatively small sample sizes. The author presents a case of duodenal adenocarcinoma in a 62-year-old male patient with a clinical manifestation of melena. Duodeno-cephalo-pancreatectomy was the surgical option.

Keywords: Adenocarcinoma; Computed tomography; Duodenum.

PubMed Disclaimer

Figures

Fig 1
Fig. 1
Upper gastrointestinal endoscopy showed an ulceration (arrow) 3 cm in diameter, with some small bleeding spots 5 cm from the papilla.
Fig 2
Fig. 2
Abdominal computed tomography scan of the duodenal bulb. A low-density nodule, 10 × 4 mm in size and fatty in appearance, is seen in the submucosal layer. No abnormal lymph nodes are seen around the stomach.
Fig 3
Fig. 3
Biopsy results for the tumor in the duodenum. Tumor cells have large, atypical nuclei and form irregular glands. The stroma is infiltrated by chronic inflammatory cells. All findings are consistent with adenocarcinoma.

References

    1. Hatzaras I, Palesty JA, Abir F, Sullivan P, Kozol RA, Dudrick SJ, Longo WE. Small-bowel tumors: epidemiologic and clinical characteristics of 1260 cases from the Connecticut tumor registry. Arch Surg. 2007;142(3):229–235. doi: 10.1001/archsurg.142.3.229. - DOI - PubMed
    1. Alwmark A, Andersson A, Lasson A. Primary carcinoma of the duodenum. Ann Surg. 1980;191(1):13–18. doi: 10.1097/00000658-198001000-00003. - DOI - PMC - PubMed
    1. Han SL, Cheng J, Zhou HZ, Zeng QQ, Lan SH. The surgical treatment and outcome for primary duodenal adenocarcinoma. J Gastrointest Cancer. 2010;41(4):243–247. doi: 10.1007/s12029-010-9160-1. - DOI - PubMed
    1. Han SL, Cheng J, Zhou HZ, Guo SC, Jia ZR, Wang PF. Surgically treated primary malignant tumor of small bowel: a clinical analysis. World J Gastroenterol. 2010;16(12):1527–1532. doi: 10.3748/wjg.v16.i12.1527. - DOI - PMC - PubMed
    1. Czaykowski P, Hui D. Chemotherapy in small bowel adenocarcinoma: 10-year experience of the British Columbia Cancer Agency. Clin Oncol (R Coll Radiol) 2007;19(2):143–149. doi: 10.1016/j.clon.2006.12.001. - DOI - PubMed

Publication types

LinkOut - more resources