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Comment
. 2023 Nov;44(11):865-867.
doi: 10.1016/j.it.2023.09.010. Epub 2023 Oct 11.

Human macrophages choreograph tissue development

Elvira Mass  1
Affiliations
Comment

Human macrophages choreograph tissue development

Elvira Mass. Trends Immunol. 2023 Nov.

Abstract

Yolk sac-derived macrophages have been described to promote organogenesis and tissue function in animal models, but the relevance of these studies for humans has been debated. Wang et al. reveal that human macrophage development follows similar developmental trajectories with functionally distinct macrophage populations across tissues as observed in mice.

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Conflict of interest statement

Declaration of interests The author declares no conflicts of interest.

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