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Review
. 2023 Sep 28;12(19):6249.
doi: 10.3390/jcm12196249.

Childhood Obesity and Congenital Heart Disease: A Lifelong Struggle

Affiliations
Review

Childhood Obesity and Congenital Heart Disease: A Lifelong Struggle

Giovanni Di Salvo et al. J Clin Med. .

Abstract

Congenital heart disease (CHD) affects approximately one in every one hundred infants worldwide, making it one of the most prevalent birth abnormalities globally. Despite advances in medical technology and treatment choices, CHD remains a significant health issue and necessitates specialized care throughout an individual's life. Childhood obesity has emerged as a novel global epidemic, becoming a major public health issue, particularly in individuals with lifelong conditions such as CHD. Obesity has profound effects on cardiac hemodynamics and morphology, emphasizing the importance of addressing obesity as a significant risk factor for cardiovascular health. Obesity-induced alterations in cardiac function can have significant implications for cardiovascular health and may contribute to the increased risk of heart-related complications in obese individuals. Moreover, while diastolic dysfunction may be less apparent in obese children compared to adults, certain parameters do indicate changes in early left ventricular relaxation, suggesting that obesity can cause cardiac dysfunction even in pediatric populations. As most children with CHD now survive into adulthood, there is also concern about environmental and behavioral health risk factors in this particular patient group. Addressing obesity in individuals with CHD is essential to optimize their cardiovascular health and overall quality of life. This review aims to succinctly present the data on the impact of obesity on CHD and to enhance awareness of this perilous association among patients, families, and healthcare providers.

Keywords: cardiac function; childhood obesity; congenital heart disease.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Andonian C., Muntean I., Mornoș C., Benedek T. Congenital heart disease in children: A narrative review. Clujul Med. 2019;92:5–12.
    1. Benjamin J.R., Irina I., Rachael W., David W.B. Cause of death in adults with congenital heart disease. Congenit. Heart Dis. 2018;13:10–16.
    1. Barbiero S.M., Palma A.M., Silva K.S., Maziero R.S., Bettiol H. Overweight, obesity, and arterial hypertension in children and adolescents. Rev. Paul. Pediatr. 2014;32:257–264. - PubMed
    1. Ogden C.L., Carroll M.D., Curtin L.R., McDowell M.A., Tabak C.J., Flegal K. Prevalence of Overweight and Obesity in the United States, 1999–2004. JAMA. 2006;295:1549–1555. doi: 10.1001/jama.295.13.1549. - DOI - PubMed
    1. Kenchaiah S., Evans J.C., Levy D., Wilson P.W., Benjamin E.J., Larson M.G., Kannel W.B., Vasan R.S. Obesity and the Risk of Heart Failure. N. Engl. J. Med. 2002;347:305–313. doi: 10.1056/NEJMoa020245. - DOI - PubMed