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. 2024 Apr;281(4):1709-1716.
doi: 10.1007/s00405-023-08273-6. Epub 2023 Oct 14.

Normal linear and non-linear cochlear mechanisms and efferent system functioning in individuals with misophonia

Urs Suraj  1 , Kavassery Venkateswaran Nisha  2 , Prashanth Prabhu  2
Affiliations

Normal linear and non-linear cochlear mechanisms and efferent system functioning in individuals with misophonia

Urs Suraj et al. Eur Arch Otorhinolaryngol. 2024 Apr.

Abstract

Background: Misophonia, a condition characterized by heightened sensitivity and strong emotional reactions to specific sounds, has sparked considerable interest and debate regarding its underlying auditory mechanisms. The study aimed to understand the auditory underpinnings of two such potential inner ear systems, non-linear and linear outer hair cell functioning along with auditory efferent functioning in individuals with misophonia.

Methods: 40 ears with misophonia (20 participants) and 37 ears without misophonia (20 participants), both having normal hearing sensitivity were included in this study. Transient evoked otoacoustic emissions (TEOAEs) and distortion product otoacoustic emissions (DPOAEs) were obtained in two conditions (with and without contralateral noise).

Results: Results of independent-samples t-test showed no statistically significant difference (p > 0.05) in the absolute amplitudes of both TEOAEs and DPOAEs between the individuals with and without misophonia. There was no statistically significant difference (p > 0.05) observed in the magnitude of suppression amplitude between the two groups for in both TEOAEs and DPOAEs between individuals with and without misophonia.

Conclusion: These results suggest that the cochlear and efferent auditory underpinnings examined in this study may not be major contributors to the development or manifestation of misophonia.

Keywords: Efferent system; Linear and non-linear; Misophonia; Otoacoustic emissions; Suppression.

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