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. 2023 Oct 13;62(10):1962-1965.
doi: 10.1515/cclm-2023-0933. Print 2024 Sep 25.

The LEAP checklist for laboratory evaluation and analytical performance characteristics reporting of clinical measurement procedures

Tze Ping Loh  1 , Brian R Cooke  2 , Thi Chi Mai Tran  3   4 , Corey Markus  5 , Rosita Zakaria  6   7 , Chung Shun Ho  8 , Elvar Theodorsson  9 , Ronda F Greaves  10   11 ; IFCC Working Group on Method Evaluation Protocols (WG-MEP)
Affiliations
Free article

The LEAP checklist for laboratory evaluation and analytical performance characteristics reporting of clinical measurement procedures

Tze Ping Loh et al. Clin Chem Lab Med. .
Free article

Abstract

Reporting a measurement procedure and its analytical performance following method evaluation in a peer-reviewed journal is an important means for clinical laboratory practitioners to share their findings. It also represents an important source of evidence base to help others make informed decisions about their practice. At present, there are significant variations in the information reported in laboratory medicine journal publications describing the analytical performance of measurement procedures. These variations also challenge authors, readers, reviewers, and editors in deciding the quality of a submitted manuscript. The International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Method Evaluation Protocols (IFCC WG-MEP) developed a checklist and recommends its adoption to enable a consistent approach to reporting method evaluation and analytical performance characteristics of measurement procedures in laboratory medicine journals. It is envisioned that the LEAP checklist will improve the standardisation of journal publications describing method evaluation and analytical performance characteristics, improving the quality of the evidence base that is relied upon by practitioners.

Keywords: emerging technology(ies); method validation; method verification.

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