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Review
. 2023 Dec:750:109786.
doi: 10.1016/j.abb.2023.109786. Epub 2023 Oct 13.

Erythrocyte glutathione transferase. A sensitive Up-Down biomarker of environmental and industrial pollution

Alessio Bocedi  1 , Giorgia Gambardella  1 , Giada Cattani  1 , Sara Notari  1 , Giorgio Ricci  2
Affiliations
Review

Erythrocyte glutathione transferase. A sensitive Up-Down biomarker of environmental and industrial pollution

Alessio Bocedi et al. Arch Biochem Biophys. 2023 Dec.

Abstract

Erythrocyte glutathione transferase is a well-known biomarker of environmental pollution. Examination of the extensive scientific literature discovers an atypical and very interesting property of this enzyme which may reveal a chronic exposition to many contaminants but in some cases even an acute and short-term dangerous contamination. This review also underlines the peculiar molecular and kinetic properties of this enzyme which makes it unique in the panorama of enzymes used as biomarker for environmental contamination.

Keywords: Animal model; Biomarker; Environmental pollution; Glutathione; Glutathione transferase; Industrial pollution.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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