Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Oct 10:16:2821-2827.
doi: 10.2147/CCID.S393254. eCollection 2023.

Improving Psychological Health Outcomes in Children with Atopic Dermatitis

Niyaz Mostafa  1 , Saxon D Smith  2
Affiliations
Review

Improving Psychological Health Outcomes in Children with Atopic Dermatitis

Niyaz Mostafa et al. Clin Cosmet Investig Dermatol. .

Abstract

Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disease that usually develops in early childhood. AD has a significant impact on quality of life and psychological health outcomes in both adults and children. There are increased reported rates of psychiatric comorbidities including anxiety, depression, ADHD and suicidal ideation compared to the general population. Primary caregivers of children with pediatric eczema and their families may also have derangements in psychological health and quality of life. A number of interventions exist for AD and address wellbeing outcomes as an important aspect of effective treatment.

Methods: A comprehensive literature search was conducted using PubMed/Medline, Embase, the Cochrane Central Register of Controlled Trials in February 2023. Published studies up to April 2023 were included related to interventions for childhood AD that included psychological health or quality of life outcomes. These interventions were stratified according to type and evidence quality.

Results: Search strategy revealed a wide variety of interventions with demonstrated improvements in quality of life or wellbeing of patients with pediatric AD or their families. Both pharmacological and non-pharmacological interventions demonstrated effectiveness in improving disease outcomes.

Conclusion: A variety of both pharmacological and non-pharmacological interventions may be employed to improve psychological health outcomes in children with AD.

Keywords: atopic dermatitis; children; eczema; pediatric; psychology; wellbeing.

PubMed Disclaimer

Conflict of interest statement

Niyaz Mostafa reports no conflicts of interest in this work. Saxon Smith is a principal investigator for ABBVIE and Sanofi Genzyme; on the advisory board for ABBVIE, Sanofi Genzyme, Pfizer and Eli Lilly; received education speaker fees from ABBVIE; received consultancy and education speaker fees from Sanofi Genzyme, Pfizer and Eli Lilly; outside the submitted work.

Similar articles

See all similar articles

References

    1. Bieber T. Atopic dermatitis. N Engl J Med. 2008;358(14):1483–1494. doi:10.1056/NEJMra074081 - DOI - PubMed
    1. Nutten S. Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab. 2015;66(Suppl 1):8–16. doi:10.1159/000370220 - DOI - PubMed
    1. Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI; ISAAC Phase Three Study Group. Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. J Allergy Clin Immunol. 2009;124(6):1251–1258.e23. doi:10.1016/j.jaci.2009.10.009 - DOI - PubMed
    1. Lifschitz C. The Impact of Atopic Dermatitis on Quality of Life. Ann Nutr Metab. 2015;66(Suppl. 1):34–40. doi:10.1159/000370226 - DOI - PubMed
    1. Xie QW, Dai X, Tang X, Chan CHY, Chan CLW. Risk of mental disorders in children and adolescents with atopic dermatitis: a systematic review and meta-analysis. Front Psychol. 2019;10:1773. doi:10.3389/fpsyg.2019.01773 - DOI - PMC - PubMed