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Review
. 2023 Nov;30(11):103814.
doi: 10.1016/j.sjbs.2023.103814. Epub 2023 Sep 26.

Botanicals against some important nematodal diseases: Ascariasis and hookworm infections

Ayyagari Ramlal  1   2 , Aparna Nautiyal  3 , Jitendra Kumar  4   5 , Vachaspati Mishra  6 , Nisha Sogan  3 , Abdel Nasser B Singab  7   8
Affiliations
Review

Botanicals against some important nematodal diseases: Ascariasis and hookworm infections

Ayyagari Ramlal et al. Saudi J Biol Sci. 2023 Nov.

Abstract

Ascariasis and intestinal parasitic nematodes are the leading cause of mass mortality infecting many people across the globe. In light of the various deleterious side effects of modern chemical-based allopathic drugs, our preferences have currently shifted towards the use of traditional plant-based drugs or botanicals for treating diseases. The defensive propensities in the botanicals against parasites have probably evolved during their co-habitation with parasites, humans and plants in nature and hence their combative interference in one another's defensive mechanisms has occurred naturally ultimately being very effective in treating diseases. This article broadly outlines the utility of plant-based compounds or botanicals prepared from various medicinal herbs that have the potential to be developed as effective therapies against the important parasites causing ascariasis and intestinal hookworm infections leading to ascariasis & infections and thereby human mortality, wherein allopathic treatments are less effective and causes enormous side-effects.

Keywords: Antiparasitic agents; Ascariasis; Drug-resistance; Intestinal hookworm; Medicinal plants; Natural compounds; Neglected tropical diseases; Nematodes.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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