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. 2023 Oct 31;59(87):13038-13041.
doi: 10.1039/d3cc04696f.

Super-resolution imaging of mitochondrial cristae using a more hydrophobic far-red Si-rhodamine probe

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Super-resolution imaging of mitochondrial cristae using a more hydrophobic far-red Si-rhodamine probe

Jing Sun et al. Chem Commun (Camb). .

Abstract

Mitochondrial probe SiRPFA was synthesized by attaching a long perfluoroalkyl chain on Si-rhodamine cationic dye. High lipophilicity endowed SiRPFA with mitochondrial membrane potential independent properties. Under stimulated emission depletion microscopy, SiRPFA clearly revealed changes in mitochondrial cristae morphology during autophagy induced by starvation or apoptosis.

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