miR-21p-5p coordinates biological pathways to promote MASLD progression
- PMID: 37846804
- DOI: 10.1111/liv.15740
miR-21p-5p coordinates biological pathways to promote MASLD progression
Keywords: PPARα; hepatocellular carcinoma (HCC); metabolic dysfunction-associated steatohepatitis (MASH); metabolic dysfunction-associated steatotic liver disease (MASLD); miR-21-5p.
Comment on
-
miR-21-5p promotes NASH-related hepatocarcinogenesis.Liver Int. 2023 Oct;43(10):2256-2274. doi: 10.1111/liv.15682. Epub 2023 Aug 3. Liver Int. 2023. PMID: 37534739
References
REFERENCES
-
- Liu J, Ayada I, Zhang X, et al. Estimating global prevalence of metabolic dysfunction-associated fatty liver disease in overweight or obese adults. Clin Gastroenterol Hepatol. 2022;20:e573-e582.
-
- Huang DQ, El-Serag HB, Loomba R. Global epidemiology of NAFLD related HCC: trends, predictions, risk factors and prevention. Nat Rev Gastroenterol Hepatol. 2021;18:223-238.
-
- Wu J, Nagy LE, Liangpunsakul S, Wang L. Non-coding RNA crosstalk with nuclear receptors in liver disease. Biochim Biophys Acta Mol Basis Dis. 2021;1867(5):166083.
-
- Agbu P, Carthew RW. MicroRNA-mediated regulation of glucose and lipid metabolism. Nat Rev Mol Cell Biol. 2021;22(6):425-438.
-
- Wang X, He Y, Mackowiak B, Gao B. MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases. Gut. 2021;70(4):784-795.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
