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. 2023 Oct 2:10:1269328.
doi: 10.3389/fcvm.2023.1269328. eCollection 2023.

Body mass index, neck circumference, and hypertension: a prospective cohort study

Tao-Jun Ren #  1   2 , Kun Zhang #  1   2 , Wen-Juan Li  3 , Shu-Tang Ren  2 , Yun-Zhou Huang  2 , Ning Yang  2 , Shou-Ling Wu  4 , Yu-Ming Li  2
Affiliations

Body mass index, neck circumference, and hypertension: a prospective cohort study

Tao-Jun Ren et al. Front Cardiovasc Med. .

Abstract

Objective: This study aimed to investigate the association between BMI combined with neck circumference and the risk of hypertension.

Methods: We selected participants from the Kailuan study in 2014 who were normotensive as our research subjects. We compared the risk of hypertension among individuals in group 1 (non-obese with low neck circumference), group 2 (non-obese with high neck circumference), group 3 (obese with low neck circumference), and group 4 (obese with high neck circumference).

Results: After a median observation period of 3.86 years, hypertension occurred in 13,383 participants. Subjects in Group 2, 3, and 4 had significantly higher risks of hypertension compared to Group 1, with hazard ratios (HRs) of 1.066 (95% CI: 1.025, 1.110), 1.322 (95% CI: 1.235, 1.415), and 1.422 (95% CI: 1.337, 1.512), respectively. Additionally, adding BMI to a conventional model had a greater incremental effect on predicting hypertension compared to adding neck circumference alone. However, considering both BMI and neck circumference together further improved the prediction of hypertension.

Conclusion: Individuals with both high BMI and high neck circumference face a higher risk of hypertension. Moreover, BMI is a superior predictor of hypertension risk compared to neck circumference, but using both of these measures can further enhance the accuracy of hypertension risk prediction.

Keywords: BMI; hypertension; kailuan; neck circumference; prospective cohort study.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer HZ declared a shared parent affiliation with the author(s) TR, KZ, STR, YH, NY, YL to the handling editor at the time of review.

Figures

Figure 1
Figure 1
Flow chart of inclusion and exclusion.
Figure 2
Figure 2
Cumulative incidence of hypertension.
Figure 3
Figure 3
Sensitivity analyses for the association of BMI and NC with the risk of hypertension.
Figure 4
Figure 4
Stratified analysis for the association of BMI and NC with the risk of hypertension.
See this image and copyright information in PMC

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