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Review
. 2023 Oct 18;15(718):eadj2166.
doi: 10.1126/scitranslmed.adj2166. Epub 2023 Oct 18.

Zoonotic mosquito-borne arboviruses: Spillover, spillback, and realistic mitigation strategies

Affiliations
Review

Zoonotic mosquito-borne arboviruses: Spillover, spillback, and realistic mitigation strategies

Rafael K Campos et al. Sci Transl Med. .

Abstract

Emerging zoonotic mosquito-borne viruses pose increasing health threats because of growing mosquito population, geographic expansions, and control challenges. We emphasize the need for global preparedness to effectively mitigate the health, societal, and economic impacts of spillover by these viruses through proactive measures of prediction, surveillance, prevention, and treatment.

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Conflict of interest statement

Competing interests: The authors declare that they have no competing interests.

Figures

Fig. 1.
Fig. 1.. Transmission cycles of zoonotic mosquito-borne viruses.
Enzootic, epizootic, and epidemic cycles of important ZMBs are shown with known or putative reservoirs, epizootic amplifiers, and important vectors. (A) Enzootic cycles. (B) Epizootic cycles. (C) Urban, human-amplified epidemic cycles. Abbreviated virus names are color-coded by family according the legend at the top. Figure based on relevant references (–5, 19).

References

    1. Kuno G, Mackenzie JS, Junglen S, Hubalek Z, Plyusnin A, Gubler DJ, Vertebrate reservoirs of arboviruses: Myth, synonym of amplifier, or reality? Viruses 9, 185 (2017). - PMC - PubMed
    1. Weaver SC, Barrett AD, Transmission cycles, host range, evolution and emergence of arboviral disease. Nat. Rev. Microbiol. 2, 789–801 (2004). - PMC - PubMed
    1. Pierson TC, Diamond MS, The continued threat of emerging flaviviruses. Nat. Microbiol. 5, 796–812 (2020). - PMC - PubMed
    1. Zaid A, Burt FJ, Liu X, Poo YS, Zandi K, Suhrbier A, Weaver SC, Texeira MM, Mahalingam S, Arthritogenic alphaviruses: Epidemiological and clinical perspective on emerging arboviruses. Lancet Infect. Dis. 21, e123–e133 (2021). - PubMed
    1. Azar SR, Campos RK, Bergren NA, Camargos VN, Rossi SL, Epidemic alphaviruses: Ecology, emergence and outbreaks. Microorganisms 8, 1167 (2020). - PMC - PubMed