The 100 Most Cited Kluver-Bucy Research Articles: A Bibliometric Analysis

Abstract

Kluver-Bucy Syndrome (KBS) is a rare neuropsychiatric disorder characterized by hyperorality, hypersexuality, bulimia, visual agnosia, and amnesia due to lesions affecting bilateral temporal lobes. It is attributed to a multitude of causes, including stroke, herpes simplex encephalitis, Alzheimer's disease, and head trauma. Current treatments for KBS include symptomatic management with antipsychotics, mood stabilizers, carbamazepine, and selective serotonin reuptake inhibitors. The bibliometric analysis was done to reflect the relevance and understanding of KBS in recent literature. The SCOPUS database was utilized to conduct a search for all articles with the terms "Kluver-Bucy" and "Kluver Bucy" from January 1, 1955 (the first available articles from the search) to February 1, 2023. The parameters included in this analysis were article title, citation numbers, citations per year, authors, institutions, publishing journals, country of origin, Source Normalized Impact per Paper, and Scopus CiteScore. Since 1937, when Kluver-Bucy Syndrome was first defined, the publications on KBS have steadily increased, with up to six publications a year in 2002. The most common institutions were SUNY Upstate Medical University, VA Medical Center, and the State University of New York (SUNY) System. Seven of these papers were published in Neurology. Almost 75% of the articles were published in journals of medicine and neuroscience. This is the first bibliometric analysis to evaluate the most influential publications about Kluver-Bucy Syndrome. A majority of the research is case-based and there is a dearth of clinical trials to identify the exact pathophysiology and physiotherapy management, possibly owing to the rarity of the disease. Our research suggests that there may be a significant overlap between Sanfilippo syndrome and KBS, suggesting that refined guidelines for establishing diagnosis may be required for children. Our study could bring a renewed interest in this field and lead to additional research focused on understanding the pathophysiology of KBS in order to promote the development of novel diagnostics and treatment.

Keywords: bibliometric analyis; kluver-bucy; kluver-bucy syndrome; medical publications; systematic review and meta analysis.

Figure 1. Chart detailing the trends of the number of publications per year from 1955 to 2015

Figure 2. Map detailing the distribution of Top Cited Articles by Country of Origin. The United States has published 58% of the top cited articles.

Created on Excel Powermap, Excel, 2023

Figure 3. Chart detailing the top affiliations of KBS articles. The most common institutions were SUNY Upstate Medical University, VA Medical Center, and the State University of New York (SUNY) System.

KBS: Kluver-Bucy Syndrome

Figure 4. Chart detailing the subject of the articles in the 100 top cited on KBS. Almost 75% of them were in medicine and neuroscience.

KBS: Kluver-Bucy Syndrome

Figure 5. Chart detailing the authors with the most papers published on Kluver-Bucy Syndrome. James A. Horel had the most publications on the subject with six articles.

Horel, J. A. [7, 21, 26, 55, 58, 94]; Ahmed, A. [67, 77, 84]; Misantone, L. J. [21, 55, 58]; Potegal, M. [67, 77, 84]; Banerjee, A. [28, 59]; Boyett, J. M. [28, 59]; Broniscer, A. [28, 59]; Burns, A. [8, 36]; Cummings, J. L. [12, 16].