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. 2023 Feb 28;14(6):534-535.
doi: 10.1136/flgastro-2022-102349. eCollection 2023.

Heart was the key to the diagnosis

Khawaja Junaid Akhtar  1 , Tina Maheswaran  1 , Christopher Watters  1   2
Affiliations

Heart was the key to the diagnosis

Khawaja Junaid Akhtar et al. Frontline Gastroenterol. .
No abstract available

Keywords: CHRONIC DIARRHOEA.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
H&E stain of colonic biopsy.
Figure 2
Figure 2
Echocardiogram.
Figure 3
Figure 3
Echocardiogram.
Figure 4
Figure 4
Cardiac MRI revealed concentric LVH and late gadolinium enhancement was suggestive of an infiltrative cardiomyopathy most likely amyloid. LVH, left ventricular hypertrophy.
Figure 5
Figure 5
Cardiac MRI revealed concentric LVH and late gadolinium enhancement was suggestive of an infiltrative cardiomyopathy most likely amyloid. LVH, left ventricular hypertrophy.
Figure 6
Figure 6
Colonic biopsy stained with Congo red demonstrating deep orange deposits of amyloid.
Figure 7
Figure 7
Apple green birefringence of the amyloid deposits under polarised light.
See this image and copyright information in PMC

References

    1. Gilstrap LG, Dominici F, Wang Y, et al. . Epidemiology of cardiac amyloidosis-associated heart failure hospitalizations among fee-for-service Medicare beneficiaries in the United States. Circ Heart Fail 2019;12:e005407. 10.1161/CIRCHEARTFAILURE.118.005407 - DOI - PMC - PubMed
    1. Palladini G, Milani P, Merlini G. Management of al amyloidosis in 2020. Blood 2020;136:2620–7. 10.1182/blood.2020006913 - DOI - PubMed

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