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. 2023 Nov 1;45(11):783-785.
doi: 10.1097/DAD.0000000000002541. Epub 2023 Sep 14.

The Intricate Relationship Between H3K27 Trimethylation and Merkel Cell Polyomavirus Status in Merkel Cell Carcinoma

Andrea Krajisnik  1 , Neda Rezaee  1 , Jessica Crystal  2 , Eleanor R Duncan  1 , Bonnie L Balzer  1 , David P Frishberg  1 , Wonwoo Shon  1
Affiliations

The Intricate Relationship Between H3K27 Trimethylation and Merkel Cell Polyomavirus Status in Merkel Cell Carcinoma

Andrea Krajisnik et al. Am J Dermatopathol. .
No abstract available

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Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Kervarrec T, Tallet A, Miquelestorena-Standley E, et al. Morphologic and immunophenotypical features distinguishing Merkel cell polyomavirus-positive and negative Merkel cell carcinoma. Mod Pathol. 2019;32:1605–1616.
    1. DeCoste RC, Carter MD, Ly TY, et al. Merkel cell carcinoma: an update. Hum Pathol. 2023;S0046-8177:00053–00059.
    1. Le Guellec S, Macagno N, Velasco V, et al. Loss of H3K27 trimethylation is not suitable for distinguishing malignant peripheral nerve sheath tumor from melanoma: a study of 387 cases including mimicking lesions. Mod Pathol. 2017;30:1677–1687.
    1. Busam K, Pulitzer MP, Coit DC, et al. Reduced H3K27me3 expression in Merkel cell polyoma virus-positive tumors. Mod Pathol. 2017;30:877–883.
    1. Matsushita M, Iwasaki T, Wardhani LO, et al. Decreased H3K27me3 expression is associated with Merkel cell polyomavirus-negative Merkel cell carcinoma, especially combined with cutaneous squamous cell carcinoma. Anticancer Res. 2019;39:5573–5579.

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