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Editorial
. 2023 Oct 19;48(5):E400-E403.
doi: 10.1503/jpn.230130. Print 2023 Sep-Oct.

Does serotonin matter in depression?

Paul R Albert  1 , Pierre Blier  2
Affiliations
Editorial

Does serotonin matter in depression?

Paul R Albert et al. J Psychiatry Neurosci. .
No abstract available

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Conflict of interest statement

Competing interests: P. Blier declares grants from AbbVie, Otsuka and Lundbeck and has received consulting fees from AbbVie, Lundbeck and Pfizer. No other competing interests were declared.

Figures

Figure 1
Figure 1
(A) Serotonin (5-HT) pathways in the brain of healthy individual and in 3 scenarios of 5-HT changes in individuals with depression with different characteristics of the 5-HT system: (B) low 5-HT synthesis, (C) low levels of postsynaptic 5-HT receptors, or (D) low levels of 5-HT reuptake transporters. The intensity of colour in projections from the raphe depicts the level of 5-HT, while colour in the ventromedial prefrontal cortex (vmPFC) depicts the level of postsynaptic 5-HT receptors. (E) The average of data from depressed individuals in images B–D showing a similar pattern to the healthy individual in image A. Created with “Serotonin Pathways in the Brain,” BioRender.com (2023) with permission. Retrieved from https://app.biorender.com/biorender-templates
See this image and copyright information in PMC

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