Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Dec;47(8):151838.
doi: 10.1016/j.semperi.2023.151838. Epub 2023 Oct 10.

Air pollution and pregnancy

Affiliations

Air pollution and pregnancy

Juan Aguilera et al. Semin Perinatol. 2023 Dec.

Abstract

Increased fossil fuel usage and extreme climate change events have led to global increases in greenhouse gases and particulate matter with 99% of the world's population now breathing polluted air that exceeds the World Health Organization's recommended limits. Pregnant women and neonates with exposure to high levels of air pollutants are at increased risk of adverse health outcomes such as maternal hypertensive disorders, postpartum depression, placental abruption, low birth weight, preterm birth, infant mortality, and adverse lung and respiratory effects. While the exact mechanism by which air pollution exerts adverse health effects is unknown, oxidative stress as well as epigenetic and immune mechanisms are thought to play roles. Comprehensive, global efforts are urgently required to tackle the health challenges posed by air pollution through policies and action for reducing air pollution as well as finding ways to protect the health of vulnerable populations in the face of increasing air pollution.

Keywords: Air pollution; Health outcomes; Maternal; Neonate; Pregnancy.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest Dr. Nadeau reports grants from National Institute of Allergy and Infectious Diseases (NIAID), National Heart, Lung, and Blood Institute (NHLBI), National Institute of Environmental Health Sciences (NIEHS), and Food Allergy Research & Education (FARE); Stock options from IgGenix, Seed Health, ClostraBio, Cour, Alladapt; Advisor at Cour Pharma; Consultant for Excellergy, Red tree ventures, Before Brands, Alladapt, Cour, Latitude, Regeneron, and IgGenix; Co-founder of Before Brands, Alladapt, Latitude, and IgGenix; National Scientific Committee member at Immune Tolerance Network (ITN), and National Institutes of Health (NIH) clinical research centers; patents include, “Mixed allergen com-position and methods for using the same,” “Granulocyte-based methods for detecting and monitoring immune system disorders,” and “Methods and Assays for Detecting and Quantifying Pure Subpopulations of White Blood Cells in Immune System Disorders”. All other authors indicate no conflict of interest

Figures

Figure 1:
Figure 1:
Increased use of fossil fuel has led to increases in greenhouse gases and pollen season length and frequency and intensity of wildfires, and sand and dust storms. Pregnant women, their fetuses and newborn infants are particularly vulnerable to adverse health effects such as maternal hypertensive disorders, postpartum depression, low birth weight, and preterm birth. In the face of worsening climate change adaptation measures (e.g., filters, masks) and mitigation measures (e.g., decreases in fossil fuel usage, increase in green spaces) are urgently needed.

References

    1. Girardi G & Bremer AA Effects of Climate and Environmental Changes on Women's Reproductive Health. Journal of Women's Health 31, 755–757 (2022). - PMC - PubMed
    1. Anderko L, Chalupka S, Du M & Hauptman M Climate Changes Reproductive and Children’s Health: A Review of Risks, Exposures, and Impacts. Pediatric Research 87, 414–419 (2020). - PubMed
    1. World Health Organization. Billions of People Still Breathe Unhealthy Air: New Who Data, <https://www.who.int/news/item/04-04-2022-billions-of-people-still-breath...> (2023).
    1. EPA. Overview of Greenhouse Gases, <https://www.epa.gov/ghgemissions/overview-greenhouse-gases> (2023).
    1. United States Environmental Protection Agency. Particulate Matter (Pm) Basics, <https://www.epa.gov/pm-pollution/particulate-matter-pm-basics#PM> (2023).