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Editorial
. 2024 Jan;26(1):101008.
doi: 10.1016/j.gim.2023.101008. Epub 2023 Oct 17.

Ready or not, genomic screening of fetuses is already here

Nina B Gold  1 , Allan Nadel  2 , Robert C Green  3
Affiliations
Editorial

Ready or not, genomic screening of fetuses is already here

Nina B Gold et al. Genet Med. 2024 Jan.
No abstract available

Keywords: Actionable disease; Genomic screening; Genomic secondary findings; Prenatal exome sequencing; Prenatal therapy.

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Conflict of interest statement

Conflict of Interest Robert C. Green has received compensation for advising the following companies: Allelica, Atria, Fabric, Genome Web, Genomic Life, Verily, VinBigData; and is co-founder of Genome Medical and Nurture Genomics. Nina B. Gold is a paid consultant for RCG Consulting.

References

    1. Mellis R, Oprych K, Scotchman E, Hill M, Chitty LS. Diagnostic yield of exome sequencing for prenatal diagnosis of fetal structural anomalies: a systematic review and meta-analysis. Prenat Diagn 2022;42(6):662–685. 10.1002/pd.6115 - DOI - PMC - PubMed
    1. Vaknin N, Azoulay N, Tsur E, et al. High rate of abnormal findings in prenatal exome trio in low risk pregnancies and apparently normal fetuses. Prenat Diagn 2022;42(6):725–735. 10.1002/pd.6077 - DOI - PubMed
    1. Van den Veyver IB, Yaron Y, Deans ZC. International Society for prenatal diagnosis 2022 debate 3-fetal genome sequencing should be offered to all pregnant patients. Prenat Diagn 2023;43(4):428–434. 10.1002/pd.6247 - DOI - PMC - PubMed
    1. Van den Veyver IB, Chandler N, Wilkins-Haug LE, Wapner RJ, Chitty LS, ISPD Board of Directors. International Society for prenatal diagnosis updated Position Statement on the use of genome-wide sequencing for prenatal diagnosis. Prenat Diagn 2022;42(6):796–803. 10.1002/pd.6157 - DOI - PMC - PubMed
    1. Nipt S-G; published December 11, 2y020. Vistara. Natera Accessed March 13, 2023. https://www.natera.com/womens-health/vistara-nipt-single-gene-test/

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