Score fluctuation might be associated with a higher placebo rate in the RAISE trial

doi:10.1016/S1474-4422(23)00364-2

Comment

. 2023 Nov;22(11):982.

doi: 10.1016/S1474-4422(23)00364-2.

Score fluctuation might be associated with a higher placebo rate in the RAISE trial

Hai-Feng Li¹, Shi-Min Hu², Jian Yin³, Huan Yang⁴

Affiliations

¹ Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: drlhf@163.com.
² Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
³ Department of Neurology, Beijing Hospital, Beijing, China.
⁴ Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

PMID: 37863601
DOI: 10.1016/S1474-4422(23)00364-2

Comment

Score fluctuation might be associated with a higher placebo rate in the RAISE trial

Hai-Feng Li et al. Lancet Neurol. 2023 Nov.

. 2023 Nov;22(11):982.

doi: 10.1016/S1474-4422(23)00364-2.

Authors

Hai-Feng Li¹, Shi-Min Hu², Jian Yin³, Huan Yang⁴

Affiliations

¹ Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: drlhf@163.com.
² Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
³ Department of Neurology, Beijing Hospital, Beijing, China.
⁴ Department of Neurology, Xiangya Hospital, Central South University, Changsha, China.

PMID: 37863601
DOI: 10.1016/S1474-4422(23)00364-2

No abstract available

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Comment in

Score fluctuation might be associated with a higher placebo rate in the RAISE trial - Authors' reply.
Howard JF Jr, Boroojerdi B, de la Borderie G, Leite MI, Utsugisawa K; RAISE Study Team. Howard JF Jr, et al. Lancet Neurol. 2023 Nov;22(11):982-983. doi: 10.1016/S1474-4422(23)00365-4. Lancet Neurol. 2023. PMID: 37863600 No abstract available.

Comment on

Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study.
Howard JF Jr, Bresch S, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Lowcock R, Vanderkelen M, Leite MI; RAISE Study Team. Howard JF Jr, et al. Lancet Neurol. 2023 May;22(5):395-406. doi: 10.1016/S1474-4422(23)00080-7. Lancet Neurol. 2023. PMID: 37059508 Clinical Trial.

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Editorial: Phenotypes of myasthenia gravis, volume II.
Li HF, Gilhus NE, Xue Q, Gao F. Li HF, et al. Front Neurol. 2023 Nov 24;14:1335308. doi: 10.3389/fneur.2023.1335308. eCollection 2023. Front Neurol. 2023. PMID: 38073651 Free PMC article. No abstract available.
Risk-Benefit Analysis of Novel Treatments for Patients with Generalized Myasthenia Gravis.
Smith AG, Wolfe GI, Habib AA, Qi CZ, Yang H, Du M, Chen X, Gelinas D, Brauer E, Phillips G, Saccà F. Smith AG, et al. Adv Ther. 2024 Dec;41(12):4628-4647. doi: 10.1007/s12325-024-03014-5. Epub 2024 Oct 29. Adv Ther. 2024. PMID: 39470879 Free PMC article.

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Score fluctuation might be associated with a higher placebo rate in the RAISE trial

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Score fluctuation might be associated with a higher placebo rate in the RAISE trial

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