A central role for mesangial cells in the initiation of diabetic nephropathy

Affiliations

¹ Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: kim.lee@mssm.edu.
³ Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Renal Section, James J. Peters Veterans Affair Medical Center, Bronx, New York, USA. Electronic address: cijiang.he@mssm.edu.

Comment

Zhengying Fang et al. Kidney Int. 2023 Nov.

. 2023 Nov;104(5):872-874.

doi: 10.1016/j.kint.2023.03.033.

¹ Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: kim.lee@mssm.edu.
³ Department of Medicine, Barbara T. Murphy Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Renal Section, James J. Peters Veterans Affair Medical Center, Bronx, New York, USA. Electronic address: cijiang.he@mssm.edu.

No abstract available

Keywords: diabetic kidney disease; glomerular hyperfiltration; mesangial cells; myocardin-related transcription factor (MRTF).

Comment on

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy.
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer MT, Nair V, Gies SE, Wu G, Nelson RG, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen CD, Delic D, Krebs CF, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber TB. Liu S, et al. Genome Med. 2023 Jan 10;15(1):2. doi: 10.1186/s13073-022-01145-4. Genome Med. 2023. PMID: 36627643 Free PMC article.