AASLD Practice Guidance on risk stratification and management of portal hypertension and varices in cirrhosis

David E Kaplan^{1

2}, Cristina Ripoll³, Maja Thiele⁴, Brett E Fortune⁵, Douglas A Simonetto⁶, Guadalupe Garcia-Tsao⁷, Jaime Bosch^{8

9}

Affiliations

¹ Department of Medicine, Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
² Gastroenterology Section, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA USA.
³ Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
⁴ Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
⁵ Department of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
⁶ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
⁷ Yale University, New Haven, USA; VA-CT Healthcare System, West Haven, CT, USA.
⁸ Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.
⁹ Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS) and CIBERehd, University of Barcelona, Spain.

Free article

David E Kaplan et al. Hepatology. 2024.

Free article

. 2024 May 1;79(5):1180-1211.

doi: 10.1097/HEP.0000000000000647. Epub 2023 Oct 23.

David E Kaplan^{1

2}, Cristina Ripoll³, Maja Thiele⁴, Brett E Fortune⁵, Douglas A Simonetto⁶, Guadalupe Garcia-Tsao⁷, Jaime Bosch^{8

9}

¹ Department of Medicine, Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
² Gastroenterology Section, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA USA.
³ Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
⁴ Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.
⁵ Department of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
⁶ Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
⁷ Yale University, New Haven, USA; VA-CT Healthcare System, West Haven, CT, USA.
⁸ Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.
⁹ Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS) and CIBERehd, University of Barcelona, Spain.

No abstract available

Comment in

New practice guidelines on risk stratification and management of portal hypertension: towards a personalized multidisciplinary approach.
Bruni A, Colecchia L, Dajti E, Barbara G, Azzaroli F. Bruni A, et al. Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):282-285. doi: 10.21037/hbsn-2024-703. Epub 2025 Mar 25. Hepatobiliary Surg Nutr. 2025. PMID: 40342763 Free PMC article. No abstract available.

1. Garcia-Tsao G, Abraldes JG, Berzigotti A, Bosch J. Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2017;65:310–335.
1. Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W. Practice Guidelines Committee of the American Association for the Study of Liver Diseases, Practice Parameters Committee of the American College of Gastroenterology. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology. 2007;46:922–938.
1. de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; on behalf of the Baveno VII Faculty. Baveno VII - renewing consensus in portal hypertension. J Hepatol. 2022;76:959–974.
1. Villanueva C, Albillos A, Genescà J, Garcia-Pagan JC, Calleja JL, Aracil C, et al. β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): A randomised, double-blind, placebo-controlled, multicentre trial. Lancet. 2019;393:1597–1608.
1. Biggins SW, Angeli P, Garcia-Tsao G, Gines P, Ling SC, Nadim MK, et al. Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2021;74:1014–1048.