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. 2023 Oct 23;18(1):78.
doi: 10.1186/s13024-023-00666-9.

cGAS-STING triggers inflammaging-associated neurodegeneration

José M Izquierdo  1
Affiliations

cGAS-STING triggers inflammaging-associated neurodegeneration

José M Izquierdo. Mol Neurodegener. .
No abstract available

Keywords: Neurodegeneration; Neuroinflammation; Neurosenescence.

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Conflict of interest statement

The author declares no competing interests.

Figures

Fig. 1
Fig. 1
cGAS-STING pathway leads to inflammation and microglia-dependent neurodegeneration. Overview of murine brain aging, homeostatic and activated microglia, induction of mitochondrial DNA leakage-dependent cGAS-STING pathway, synthesis of type I IFN and proinflammatory cytokines during loss of homeostasis, leading to neurodegeneration
See this image and copyright information in PMC

References

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