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[Preprint]. 2023 Oct 12:2023.10.11.561890.
doi: 10.1101/2023.10.11.561890.

Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer

Jessica Spring, Sandeep Gurbuxani, Tatyana Golovkina

Microbiota may affect the tumor type but not overall tumor development in two models of heritable cancer

Jessica Spring et al. bioRxiv. .

Update in

Abstract

Microbial impact on tumorigenesis of heritable cancers proximal to the gut is well documented. Whether the microbiota influences cancers arising from inborn mutations at sites distal to the gut is undetermined. Using two models of heritable cancer, we found the microbiota to be inconsequential for tumor development. However, the type of tumor that develops may be influenced by the microbiota. This work furthers our understanding of the microbial impact on tumor development.

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