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Randomized Controlled Trial
. 2024 Apr;28(2):182-191.
doi: 10.1111/1744-9987.14076. Epub 2023 Oct 24.

Effect of intradialytic weight resistance training exercise in sarcopenic hemodialysis patients: A randomized controlled trial

Chokchai Chaovarin  1 , Amnart Chaiprasert  1 , Bancha Satirapoj  1 , Naowanit Nata  1 , Wisit Kaewput  1 , Theerasak Tangwonglert  1 , Narittaya Varothai  1 , Paramat Thimachai  1 , Pamila Tasanavipas  1 , Pitchamon Inkong  1 , Narongrit Siriwattanasit  1 , Natthaya Khrongkab  1 , Ouppatham Supasyndh  2
Affiliations
Randomized Controlled Trial

Effect of intradialytic weight resistance training exercise in sarcopenic hemodialysis patients: A randomized controlled trial

Chokchai Chaovarin et al. Ther Apher Dial. 2024 Apr.

Abstract

Background: Sarcopenia has a high prevalence in end-stage kidney disease (ESKD). However, there is limited evidence of resistance exercise in these patients.

Objective: The study investigated the effects of resistance exercise on muscle mass, strength, and physical functioning.

Method: Fifty-three patients were randomly assigned to resistance training exercise (n = 26) and standard exercise (n = 27) groups. All of the patients were diagnosed with sarcopenia by the Asian Working Group for Sarcopenia 2019 criteria.

Results: After 12 weeks, an improvement in leg muscle strength was significantly greater in the resistant exercise group compared with standard exercise (12.19 vs. 2.83 kg, p < 0.001). Appendicular skeletal muscle mass had a mean difference (1.01 vs. 1.02 kg/m2 , p = 0.96). Physical performance status had a mean difference (-2.3 vs. -18 s, p = 0.42). There were no serious adverse events.

Conclusion: Over a 12-week follow-up, resistance exercise improved muscle strength in sarcopenic ESKD patients. Muscle mass and physical performance showed no significant change, but there is still a trend demonstrating to improve.

Keywords: hemodialysis; resistance exercise; sarcopenia.

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References

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