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Review
. 2023 Oct 9;185(41):V04230237.

Platform trials

[Article in Danish]
Anders Perner  1   2 , Maj-Brit N Kjær  1 , Hans-Christian Thorsen-Meyer  1 , Benjamin S Kaas-Hansen  1   3 , Marie W Munch  1 , Marie O Collet  1 , Camilla Rl Bruun  1 , Aksel Kg Jensen  3 , Theis Lange  4 , Trine Albertsen  5 , Claus Duedal Pedersen  5 , Lone M Poulsen  6 , Ole Mathiesen  2   6 , Anne C Brøchner  7 , Thomas Strøm  8   9 , Lars W Andersen  10 , Steffen Christensen  11 , Bodil S Rasmussen  12 , Olav L Schjørring  12 , Mathias Maagaard  5 , Morten Hylander Møller  1   2 , Anders Granholm  1
Affiliations
  • PMID: 37873986
Free article
Review

Platform trials

[Article in Danish]
Anders Perner et al. Ugeskr Laeger. .
Free article

Abstract

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

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