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Review
. 2023 Nov;25(11):1475-1488.
doi: 10.1007/s11886-023-01961-z. Epub 2023 Oct 24.

Emerging Medical Therapies for the Treatment of Obesity in Women with Cardiovascular Diseases

Leili Behrooz  1 , Carrie G Lenneman  2 , Naomi M Hamburg  3
Affiliations
Review

Emerging Medical Therapies for the Treatment of Obesity in Women with Cardiovascular Diseases

Leili Behrooz et al. Curr Cardiol Rep. 2023 Nov.

Abstract

Purpose of review: In this review, the impact of obesity on cardiovascular disease in women and emerging anti-obesity pharmacologic treatments are discussed.

Recent findings: Robust evidence demonstrates the burden of obesity across the lifespan in women and links obesity to a diverse set of cardiovascular diseases. Female-specific risk factors including sex hormones and pregnancy factors intersect with obesity and cardiovascular risk. Sustained weight loss has potential for cardiovascular benefits. Recent trials demonstrate cardiovascular benefits of emerging agents with weight loss effects including GLP-1 RA and SGLT2 inhibitors in women. Treatment and prevention strategies for cardiovascular disease in obese women should include integration of weight management strategies including the targeted use of emerging pharmacologic therapies.

Keywords: Cardiovascular disease; Obesity; Prevention; Risk factors; Women.

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Conflict of interest statement

Dr. Hamburg has done consulting for Novo Nordisk. The other authors have nothing to disclose.

Figures

Fig. 1
Fig. 1
Impact of obesity on cardiovascular disease across the lifespan in women. Created with BioRender.com
See this image and copyright information in PMC

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