Cohort Profile Update: Project Viva mothers

Sheryl L Rifas-Shiman¹, Izzuddin M Aris¹, Karen M Switkowski¹, Jessica Young¹, Abby F Fleisch^{2

3}, Tamarra James-Todd^{4

5}, Ami R Zota⁶, Wei Perng⁷, Marie-France Hivert^{1

8}, Janet W Rich-Edwards^{5

9

10}, Melissa Perez Capotosto¹¹, Jorge E Chavarro^{5

9

12}, Emily Oken^{1

12}

Affiliations

¹ Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
² Pediatric Endocrinology and Diabetes, Maine Medical Center, Portland, ME, USA.
³ Center for Interdisciplinary Population and Health Research, MaineHealth Institute for Research, Portland, ME, USA.
⁴ Department of Environmental Health, Harvard T H Chan School of Public Health, Boston, MA, USA.
⁵ Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.
⁶ Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
⁷ Department of Epidemiology and the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
⁸ Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
⁹ Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
¹⁰ Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA.
¹¹ William F. Connell School of Nursing, Boston College, Boston, MA, USA.
¹² Department of Nutrition, Harvard T H Chan School of Public Health, Boston, MA, USA.

PMID: 37875013
PMCID: PMC10749767
DOI: 10.1093/ije/dyad137

Cohort Profile Update: Project Viva mothers

Sheryl L Rifas-Shiman et al. Int J Epidemiol. 2023.

. 2023 Dec 25;52(6):e332-e339.

doi: 10.1093/ije/dyad137.

Authors

Affiliations

¹ Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
² Pediatric Endocrinology and Diabetes, Maine Medical Center, Portland, ME, USA.
³ Center for Interdisciplinary Population and Health Research, MaineHealth Institute for Research, Portland, ME, USA.
⁴ Department of Environmental Health, Harvard T H Chan School of Public Health, Boston, MA, USA.
⁵ Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.
⁶ Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.
⁷ Department of Epidemiology and the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
⁸ Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.
⁹ Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
¹⁰ Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA.
¹¹ William F. Connell School of Nursing, Boston College, Boston, MA, USA.
¹² Department of Nutrition, Harvard T H Chan School of Public Health, Boston, MA, USA.

PMID: 37875013
PMCID: PMC10749767
DOI: 10.1093/ije/dyad137

No abstract available

PubMed Disclaimer

Conflict of interest statement

None declared.

Figures

**Figure 1**
Flow of Project Viva mothers’ involvement through the Mid-Life Visit. ^aCumulative number disenrolled from birth to visit. ^bIneligible for visit because no information on diet in pregnancy. We adapted Figure 1 from our original cohort profile

See this image and copyright information in PMC

Cited by

Cohort Profile Update: Project Viva Offspring.
Rifas-Shiman SL, Aris IM, Switkowski KM, Young J, Fleisch AF, Perng W, Chavarro JE, Cardenas A, Gold DR, Zhang M, James P, Whooten RC, Kleinman KP, Oken E, Hivert MF. Rifas-Shiman SL, et al. Int J Epidemiol. 2024 Oct 13;53(6):dyae162. doi: 10.1093/ije/dyae162. Int J Epidemiol. 2024. PMID: 39657066 No abstract available.
Associations of PFAS concentrations during pregnancy and midlife with bone health in midlife: Cross-sectional and prospective findings from Project Viva.
Lin PD, Cardenas A, Rokoff LB, Rifas-Shiman SL, Zhang M, Botelho J, Calafat AM, Gold DR, Zota AR, James-Todd T, Hauser R, Webster TF, Oken E, Fleisch AF. Lin PD, et al. Environ Int. 2024 Dec;194:109177. doi: 10.1016/j.envint.2024.109177. Epub 2024 Dec 1. Environ Int. 2024. PMID: 39667063 Free PMC article.
Pregnancy Metal Mixtures and Blood Pressure and Hypertension in Mid-Life: A Prospective U.S. Cohort Study.
Zhang M, Aris IM, Cardenas A, Rifas-Shiman SL, Lin PD, Ngo LH, Oken E, Hivert MF, Juraschek SP. Zhang M, et al. Hypertension. 2025 Apr;82(4):640-651. doi: 10.1161/HYPERTENSIONAHA.124.23980. Epub 2025 Mar 6. Hypertension. 2025. PMID: 40048682
Early-pregnancy per- and polyfluoroalkyl substances and maternal post-pregnancy weight trajectory.
Burdeau JA, Stephenson BJK, Aris IM, Mahalingaiah S, Chavarro JE, Preston EV, Hivert MF, Oken E, Calafat AM, Rifas-Shiman SL, Zota AR, James-Todd T. Burdeau JA, et al. Obesity (Silver Spring). 2025 Apr;33(4):807-816. doi: 10.1002/oby.24250. Epub 2025 Mar 12. Obesity (Silver Spring). 2025. PMID: 40074682
Neighborhood Vulnerability and Age of Natural Menopause and Menopausal Symptoms Among Midlife Women.
Lin Z, Rifas-Shiman SL, Perng W, Capotosto MP, Shifren JL, Joffe H, Hivert MF, Chavarro JE, Oken E, Aris IM. Lin Z, et al. JAMA Netw Open. 2025 May 1;8(5):e2512075. doi: 10.1001/jamanetworkopen.2025.12075. JAMA Netw Open. 2025. PMID: 40402495 Free PMC article.

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References

1. Oken E, Baccarelli AA, Gold DR. et al. Cohort profile: project viva. Int J Epidemiol 2015;44:37–48. - PMC - PubMed
1. American Psychological Association. APA Dictionary of Psychology. https://dictionary.apa.org/mid-life-crisis (19 May 2023, date last accessed).
1. Tylavsky FA, Ferrara A, Catellier DJ. et al. Understanding childhood obesity in the US: the NIH environmental influences on child health outcomes (ECHO) program. Int J Obes (Lond) 2020;44:617–27. - PMC - PubMed
1. Patro Golab B, Santos S, Voerman E. et al.; MOCO Study Group Authors. Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis. Lancet Child Adolesc Health 2018;2:812–21. - PMC - PubMed
1. Korevaar TIM, Derakhshan A, Taylor PN. et al.; Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth. Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis. JAMA 2019;322:632–41. - PMC - PubMed

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Cohort Profile Update: Project Viva mothers

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Cohort Profile Update: Project Viva mothers

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