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Case Reports
. 2023 Jul 26;25(3):155-157.
doi: 10.1016/j.ccrj.2023.06.005. eCollection 2023 Sep.

Pfizer BNT 162b2 COVID-19 vaccine-induced fulminant myopericarditis: A case study

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Case Reports

Pfizer BNT 162b2 COVID-19 vaccine-induced fulminant myopericarditis: A case study

Natalie L Montarello et al. Crit Care Resusc. .

Abstract

The use of mRNA COVID-19 vaccine can on rare occasions cause life-threatening, fulminant myopericarditis. This case report demonstrates previously reported benefit of early use of venoarterial extracorporeal membrane oxygenation mechanical assistance and supports the use of intravenous highly purified immunoglobulin pharmacotherapy to help achieve a good clinical outcome.

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Figures

Figure
Fig.1
(a) Short tau inversion recovery image: Patchy oedema of the anteroseptal and inferolateral wall. (c) T2-mapping image: myocardial oedema in the anterior and inferior walls. (b) and (d) Patchy epicardial and mid myocardial late gadolinium enhancement of the anteroseptum and inferolateral wall (b), anterior and inferior walls (d).

References

    1. Ferreira V.M., Schulz-Menger J., Holmvang G., Kramer C.M., Carbone I., Sechtem U., et al. Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations. J Am Coll Cardiol. 2018;72(24):3158–3176. - PubMed
    1. Gargano J.W., Wallace M., Hadler S.C., Langley G., Su J.R., Oster M.E., et al. Use of mRNA COVID-19 vaccine after reports of myocarditis among vaccine recipients: update from the advisory committee on immunization practices - United States, june 2021. MMWR Morb Mortal Wkly Rep. 2021;70(27):977–982. - PMC - PubMed
    1. Truong D.T., Dionne A., Muniz J.C., McHugh K.E., Portman M.A., Lambert L.M., et al. Clinically suspected myocarditis temporally related to COVID-19 vaccination in adolescents and young adults: suspected myocarditis after COVID-19 vaccination. Circulation. 2022;145(5):345–356. - PubMed
    1. Verma A.K., Lavine K.J., Lin C.Y. Myocarditis after covid-19 mRNA vaccination. N Engl J Med. 2021;385(14):1332–1334. - PMC - PubMed
    1. Brucato A., Imazio M., Gattorno M., Lazaros G., Maestroni S., Carraro M., et al. Effect of anakinra on recurrent pericarditis among patients with colchicine resistance and corticosteroid dependence: the AIRTRIP randomized clinical trial. JAMA. 2016;316(18):1906–1912. - PubMed

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