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. 2023 Nov;29(11):2362-2365.
doi: 10.3201/eid2911.231080.

Trends of Enterovirus D68 Concentrations in Wastewater, California, USA, February 2021-April 2023

Alexandria B Boehm, Debra A Wadford, Bridgette Hughes, Dorothea Duong, Alice Chen, Tasha Padilla, Chelsea Wright, Lisa Moua, Teal Bullick, Maria Salas, Christina Morales, Bradley J White, Carol A Glaser, Duc J Vugia, Alexander T Yu, Marlene K Wolfe

Trends of Enterovirus D68 Concentrations in Wastewater, California, USA, February 2021-April 2023

Alexandria B Boehm et al. Emerg Infect Dis. 2023 Nov.

Abstract

In this retrospective study, we measured enterovirus D68 (EV-D68) genomic RNA in wastewater solids longitudinally at 2 California, USA, wastewater treatment plants twice per week for 26 months. EV-D68 RNA was undetectable except when concentrations increased from mid-July to mid-December 2022, which coincided with a peak in confirmed EV-D68 cases.

Keywords: California; EV-D68; United States; acute flaccid myelitis; concentrations; enterovirus D68; respiratory infections; trends; viruses; wastewater; zoonoses.

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Figures

Figure
Figure
Enterovirus D68 RNA concentrations in wastewater solids from 2 wastewater treatment plants, California, USA. A, B) San Jose plant (A), serving 1.5 million persons in Santa Clara County, and Oceanside plant (B), serving 250,000 persons in San Francisco County. Error bars indicate SDs. Black lines indicate 5-sample trimmed means and are shown for data visualization purposes only. C) Weekly and state-aggregated laboratory-confirmed enterovirus D68 cases in California.
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