Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis

doi:10.1007/s11695-023-06866-y

Meta-Analysis

. 2023 Dec;33(12):4080-4102.

doi: 10.1007/s11695-023-06866-y. Epub 2023 Oct 25.

Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis

Ali Esparham¹, Soheil Ahmadyar¹, Tooraj Zandbaf², Amin Dalili³, Alireza Rezapanah³, Robert Rutledge⁴, Zhamak Khorgami^{5

6}

Affiliations

¹ Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
² Department of General Surgery, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.
³ Department of General Surgery, School of Medicine, Surgical Oncology Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
⁴ Center for Laparoscopic Obesity Surgery, 6240 N Durango Dr STE 120, Las Vegas, NV, 89149, USA.
⁵ Department of Surgery, University of Oklahoma School of Community Medicine, 1919 S. Wheeling Avenue, Suite 600, Tulsa, OK, 74104-5638, USA. zhamak-khorgami@ouhsc.edu.
⁶ Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. zhamak-khorgami@ouhsc.edu.

PMID: 37880462
DOI: 10.1007/s11695-023-06866-y

Meta-Analysis

Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis

Ali Esparham et al. Obes Surg. 2023 Dec.

. 2023 Dec;33(12):4080-4102.

doi: 10.1007/s11695-023-06866-y. Epub 2023 Oct 25.

Authors

Ali Esparham¹, Soheil Ahmadyar¹, Tooraj Zandbaf², Amin Dalili³, Alireza Rezapanah³, Robert Rutledge⁴, Zhamak Khorgami^{5

6}

Affiliations

¹ Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
² Department of General Surgery, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.
³ Department of General Surgery, School of Medicine, Surgical Oncology Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
⁴ Center for Laparoscopic Obesity Surgery, 6240 N Durango Dr STE 120, Las Vegas, NV, 89149, USA.
⁵ Department of Surgery, University of Oklahoma School of Community Medicine, 1919 S. Wheeling Avenue, Suite 600, Tulsa, OK, 74104-5638, USA. zhamak-khorgami@ouhsc.edu.
⁶ Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. zhamak-khorgami@ouhsc.edu.

PMID: 37880462
DOI: 10.1007/s11695-023-06866-y

Abstract

This systematic review and meta-analysis aimed to investigate the incidence of new-onset gastroesophageal reflux, reflux change, esophagitis, Barrett's esophagus, and revision due to reflux, gastritis, and marginal ulcer after one-anastomosis gastric bypass (OAGB). We performed subgroup analyses based on primary and revisional OAGB and time of follow-up. Meta-analysis of 87 studies with 27,775 patients showed a 6% rate of new-onset reflux after OAGB. Preoperative reflux status did not change significantly after OAGB. The rate of esophagitis and Barrett's esophagus was 15% and 1%, respectively. The new-onset reflux rate after OAGB was significantly higher than gastric bypass but not different with sleeve gastrectomy. The current study showed a relatively low rate of reflux and its complications after OAGB, but it was significantly higher than Roux-en-Y gastric bypass.

Keywords: Barrett’s esophagus; Esophagitis; GERD; Gastroesophageal reflux; Marginal ulcer; Mini gastric bypass; One-anastomosis gastric bypass; Reflux.

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References

1. Angrisani L, Santonicola A, Iovino P, Vitiello A, Higa K, Himpens J, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94. - PubMed - DOI
1. Rutledge R, Kular K, Manchanda N. The mini-gastric bypass original technique. Int J Surg. 2019;61:38–41. - PubMed - DOI
1. Mahawar KK, Kumar P, Carr WR, Jennings N, Schroeder N, Balupuri S, et al. Current status of mini-gastric bypass. J Minim Access Surg. 2016;12(4):305. - PubMed - PMC - DOI
1. De Luca M, Tie T, Ooi G, Higa K, Himpens J, Carbajo M-A, et al. Mini gastric bypass-one anastomosis gastric bypass (MGB-OAGB)-IFSO position statement. Obes Surg. 2018;28:1188–206. - PubMed - DOI
1. Fuchs K-H, Maroske J, Fein M, Tigges H, Ritter MP, Heimbucher J, et al. Variability in the composition of physiologic duodenogastric reflux. J Gastrointest Surg. 1999;3(4):389–96. - PubMed - DOI

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[1] Angrisani L, Santonicola A, Iovino P, Vitiello A, Higa K, Himpens J, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94. - PubMed - DOI

[2] Angrisani L, Santonicola A, Iovino P, Vitiello A, Higa K, Himpens J, et al. IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94. - PubMed - DOI

[3] Rutledge R, Kular K, Manchanda N. The mini-gastric bypass original technique. Int J Surg. 2019;61:38–41. - PubMed - DOI

[4] Rutledge R, Kular K, Manchanda N. The mini-gastric bypass original technique. Int J Surg. 2019;61:38–41. - PubMed - DOI

[5] Mahawar KK, Kumar P, Carr WR, Jennings N, Schroeder N, Balupuri S, et al. Current status of mini-gastric bypass. J Minim Access Surg. 2016;12(4):305. - PubMed - PMC - DOI

[6] Mahawar KK, Kumar P, Carr WR, Jennings N, Schroeder N, Balupuri S, et al. Current status of mini-gastric bypass. J Minim Access Surg. 2016;12(4):305. - PubMed - PMC - DOI

[7] De Luca M, Tie T, Ooi G, Higa K, Himpens J, Carbajo M-A, et al. Mini gastric bypass-one anastomosis gastric bypass (MGB-OAGB)-IFSO position statement. Obes Surg. 2018;28:1188–206. - PubMed - DOI

[8] De Luca M, Tie T, Ooi G, Higa K, Himpens J, Carbajo M-A, et al. Mini gastric bypass-one anastomosis gastric bypass (MGB-OAGB)-IFSO position statement. Obes Surg. 2018;28:1188–206. - PubMed - DOI

[9] Fuchs K-H, Maroske J, Fein M, Tigges H, Ritter MP, Heimbucher J, et al. Variability in the composition of physiologic duodenogastric reflux. J Gastrointest Surg. 1999;3(4):389–96. - PubMed - DOI

[10] Fuchs K-H, Maroske J, Fein M, Tigges H, Ritter MP, Heimbucher J, et al. Variability in the composition of physiologic duodenogastric reflux. J Gastrointest Surg. 1999;3(4):389–96. - PubMed - DOI

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Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis

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Does One-Anastomosis Gastric Bypass Expose Patients to Gastroesophageal Reflux: a Systematic Review and Meta-analysis

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