Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Oct 17;13(5):1244-1252.
doi: 10.3390/clinpract13050112.

The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie's Disease: Results from a Comparative Study

Tommaso Cai  1   2 , Marco Capece  3 , Carlo Ceruti  4 , Daniele Tiscione  1 , Marco Puglisi  1 , Paolo Verze  5 , Paolo Gontero  4 , Alessandro Palmieri  3
Affiliations

The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie's Disease: Results from a Comparative Study

Tommaso Cai et al. Clin Pract. .

Abstract

Background: Peyronie's disease (PD) represents a challenging urological disease, due to not optimal post-operative surgical outcomes. We aim to retrospectively evaluate if vacuum erection device (VED) treatment before penile curvature surgery is able to improve post-operative surgical outcomes.

Methods: All enrolled patients were assigned to the following groups: (a) the treatment group: VED treatment (three times per week) starting 3 months before surgery and (three times per week) one month after surgery; and (b) the control group: VED treatment (three times per week) one month after surgery. Follow-up urologic visits were scheduled for 3 and 6 months after surgery, and the two groups were compared.

Results: A total of 38 patients were enrolled (median age 67 years, 57-74, IQR): 20 in the treatment group and 18 in the control group. At the follow-up visits, the two groups were different in terms of IIEF-5 (26 vs. 24; p = 0.02), "yes" to SEP2 and 3 (85% vs. 55%; p < 0.001, 85% vs. 50%; p < 0.001, respectively), and PDQ (-16 vs. -11; p = 0.03). Complete correction of penile curvature was achieved in 36 patients (94.7%). In the treatment group, no hourglass deformity was reported, whereas one patient reported a mild hourglass deformity in the control group. In the treatment group, we obtained a longer total penile length (median +1.5 cm). The overall satisfaction rate was 98% in the treatment group and 96% in the control group.

Conclusions: The VED treatment before penile curvature surgery in patients affected by PD was able to improve surgical outcomes.

Keywords: Peyronie’s disease; penile curvature; quality of life; surgery; vacuum erection devices.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The figure shows the study schedule. IIEF-5: International Index of Erectile Function Questionnaire; SEP: the Sexual Encounter Profile; PRO: Patient Reported Ouitcome.
See this image and copyright information in PMC

References

    1. Moisés da Silva G.V., Dávila F.J., Rosito T.E., Martins F.E. Global Perspective on the Management of Peyronie’s Disease. Front. Reprod. Health. 2022;4:863844. doi: 10.3389/frph.2022.863844. - DOI - PMC - PubMed
    1. Kadioglu A., Dincer M., Salabas E., Culha M.G., Akdere H., Cilesiz N.C. A Population-Based Study of Peyronie’s Disease in Turkey: Prevalence and Related Comorbidities. Sex. Med. 2020;8:679–685. doi: 10.1016/j.esxm.2020.09.002. - DOI - PMC - PubMed
    1. Stuntz M., Perlaky A., des Vignes F., Kyriakides T., Glass D. The Prevalence of Peyronie’s Disease in the United States: A Population-Based Study. PLoS ONE. 2016;11:e0150157. doi: 10.1371/journal.pone.0150157. - DOI - PMC - PubMed
    1. Ainayev Y., Zhanbyrbekuly U., Gaipov A., Suleiman M., Kadyrzhanuly K., Kissamedenov N., Zhaparov U., Akhmetov D., Khairli G. Surgical Reconstruction of Penile Curvature due to Peyronie’s Disease by Plaque Incision and Buccal Mucosa Graft. J. Sex. Med. 2021;18:1308–1316. doi: 10.1016/j.jsxm.2021.04.009. - DOI - PubMed
    1. Milenkovic U., Ilg M.M., Cellek S., Albersen M. Pathophysiology and Future Therapeutic Perspectives for Resolving Fibrosis in Peyronie’s Disease. Sex. Med. Rev. 2019;7:679–689. doi: 10.1016/j.sxmr.2019.02.004. - DOI - PubMed

LinkOut - more resources