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Review
. 2023 Oct 9;14(10):500.
doi: 10.3390/jfb14100500.

The Use of Graphene Oxide in Orthodontics-A Systematic Review

Joanna Rygas  1 , Jacek Matys  2   3 , Magdalena Wawrzyńska  4 , Maria Szymonowicz  4 , Maciej Dobrzyński  5
Affiliations
Review

The Use of Graphene Oxide in Orthodontics-A Systematic Review

Joanna Rygas et al. J Funct Biomater. .

Abstract

Background: Graphene-based materials have great prospects for application in dentistry and medicine due to their unique properties and biocompatibility with tissues. The literature on the use of graphene oxide in orthodontic treatment was reviewed.

Methods: This systematic review followed the PRISMA protocol and was conducted by searching the following databases: PubMed, Scopus, Web of Science, and Cochrane. The following search criteria were used to review the data on the topic under study: (Graphene oxide) AND (orthodontic) ALL FIELDS. For the Scopus database, results were narrowed to titles, authors, and keywords. A basic search structure was adopted for each database. Initially, a total of 74 articles were found in the considered databases. Twelve articles met the inclusion criteria and were included in the review.

Results: Nine studies demonstrated the antibacterial properties of graphene oxide, which can reduce the demineralization of enamel during orthodontic treatment. Seven studies showed that it is biocompatible with oral tissues. Three studies presented that graphene oxide can reduce friction in the arch-bracket system. Two studies showed that it can improve the mechanical properties of orthodontic adhesives by reducing ARI (Adhesive Remnant Index). Three studies demonstrated that the use of graphene oxide in the appropriate concentration can also increase the SBS (shear bond strength) parameter. One research study showed that it can increase corrosion resistance. One research study suggested that it can be used to accelerate orthodontic tooth movement.

Conclusion: The studies included in the systematic review showed that graphene oxide has numerous applications in orthodontic treatment due to its properties.

Keywords: adhesive remnant index; antibacterial effect; corrosion resistance; demineralization; shear bond strength; white spots.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The figure illustrates the structural composition of graphene, graphene oxide (GO), and reduced graphene oxide (rGO) (created with Canva.com (accessed on 1 September 2023)).
Figure 2
Figure 2
The diagram illustrates three distinct antibacterial mechanisms of graphene oxide (created with Canva.com (accessed on 1 September 2023)).
Figure 3
Figure 3
The PRISMA 2020 flow diagram [25].
Figure 4
Figure 4
Figure illustrates the use of graphene oxide in orthodontic treatment (created with Canva.com (accessed on 1 September 2023)).
Figure 5
Figure 5
Distribution of bias risk of eligible studies (created with RevMan Web, Cochrane, UK).
See this image and copyright information in PMC

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