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Editorial
. 2023 Nov-Dec;75(6):391-397.
doi: 10.1016/j.ihj.2023.10.007. Epub 2023 Oct 26.

Anti-inflammatory therapy in atherosclerotic cardiovascular disease: Current reappraisal

Subrat Muduli  1 , Mohit D Gupta  2 , Girish Mp  1 , Rakesh Yadav  3
Affiliations
Editorial

Anti-inflammatory therapy in atherosclerotic cardiovascular disease: Current reappraisal

Subrat Muduli et al. Indian Heart J. 2023 Nov-Dec.
No abstract available

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Figures

Fig. 1
Fig. 1
Residual Inflammatory CV Risk and Results of the studies targeting the pathway. AFCAPS/TexCAPS; Air Force/Texas Coronary atherosclerosis prevention Study, PROVE-IT; The PRavastatin Or atorVastatin Evaluation and Infection Therapy, IMPROVE-IT; Improved Reduction of Outcomes: Vytorin Efficacy International Trial, JUPITER; Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin, CANTOS; Canakinumab Anti-Inflammatory Thrombosis Outcome Study, ASSAIL-MI Assessing the Effect of Anti‐IL‐6 Treatment in Myocardial Infarction, LoDoCo; Low Dose Colchicine, COLCOT Colchicine Cardiovascular Outcomes Trial. MACE-Major Adverse Cardiovascular Events, CAD-Coronary Artery Disease, CV- Cardiovascular.
Fig. 2
Fig. 2
NLRP3 inflammasome to hsCRP inflammatory pathway and drug targets at various levels. NLRP- Nucleotide-binding oligomerization domain Leucine rich Repeat and Pyrin domain containing, ASC- Apoptosis-associated speck-like protein containing a caspase activation and recruitment domain, IL-1-Interleukin 1, CRP-C reactive Protein, PAI- Plasminogen Activator Inhibitor.
See this image and copyright information in PMC

References

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