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. 2023 Oct 23;10(10):1720.
doi: 10.3390/children10101720.

Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors

Paulina Behrendt  1 , Michael Boettcher  1   2 , Kira Tabea Zierke  1 , Safiullah Najem  1 , Holger Zapf  3 , Konrad Reinshagen  1 , Wilhelm Wößmann  3 , Johannes Boettcher  4
Affiliations

Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors

Paulina Behrendt et al. Children (Basel). .

Abstract

(1) Background: Embryonal abdominal tumors are one of the most common entities of solid childhood cancer. The present study investigates the Health-Related Quality of Life (HRQoL) and the mental health of children to obtain a comprehensive picture of their health status and uncover a possible gap in healthcare. (2) Methods: The sample consisted of 54 children who were treated for embryonal abdominal tumors and a control group of 46 children who received uncomplicated outpatient surgery. The HRQoL and the mental health were assessed by the parent proxy reports of the questionnaires Pediatric Quality of Life Inventory (PedsQL) and Strengths and Difficulties Questionnaire (SDQ). (3) Results: Children with embryonal abdominal tumors showed significantly lower HRQoL and mental health values compared to the norm data. The index group showed lower values in the social subscales of HRQoL and mental health compared to the control group. (4) Conclusions: Embryonal abdominal tumors affect the well-being of children. There is still a gap in healthcare due to children's HRQoL and mental health, especially regarding social development. It is essential to further advance the psychological care of children and improve their chances to develop social relationships.

Keywords: embryonal abdominal tumors; health-related quality of life; mental health; pediatric surgery; rare diseases.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
CONSORT flow diagram.
See this image and copyright information in PMC

References

    1. Vogt K., Ho K. Rare disease in the time of COVID-19: Once forgotten, always forgotten? BMJ. 2020
    1. Frank M., Eidt-Koch D., Aumann I., Reimann A., Wagner T.O., Graf von der Schulenburg J.M. Measures to improve the health situation of patients with rare diseases in Germany. A comparison with the National Action Plan. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014;57:1216–1223. doi: 10.1007/s00103-014-2040-2. - DOI - PubMed
    1. Linder L.A., Hooke M.C. Symptoms in Children Receiving Treatment for Cancer-Part II: Pain, Sadness, and Symptom Clusters. J. Pediatr. Oncol. Nurs. 2019;36:262–279. doi: 10.1177/1043454219849578. - DOI - PMC - PubMed
    1. de Paula Silva N., de Souza Reis R., Garcia Cunha R., Pinto Oliveira J.F., Santos M.d.O., Pombo-de-Oliveira M.S., de Camargo B. Maternal and Birth Characteristics and Childhood Embryonal Solid Tumors: A Population-Based Report from Brazil. PLoS ONE. 2016;11:e0164398. doi: 10.1371/journal.pone.0164398. - DOI - PMC - PubMed
    1. Dharssi S., Wong-Rieger D., Harold M., Terry S. Review of 11 national policies for rare diseases in the context of key patient needs. Orphanet J. Rare Dis. 2017;12:63. doi: 10.1186/s13023-017-0618-0. - DOI - PMC - PubMed

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