Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Oct 15;12(20):6532.
doi: 10.3390/jcm12206532.

Long-Term Follow-Up of Empirical Slow Pathway Ablation in Pediatric and Adult Patients with Suspected AV Nodal Reentrant Tachycardia

Affiliations

Long-Term Follow-Up of Empirical Slow Pathway Ablation in Pediatric and Adult Patients with Suspected AV Nodal Reentrant Tachycardia

Marta Telishevska et al. J Clin Med. .

Abstract

Background: The aim of this study was to assess long-term efficacy and safety of empirical slow pathway (ESP) ablation in pediatric and adult patients with a special interest in patients without dual AV nodal physiology (DAVNP).

Methods: A retrospective single-center review of patients who underwent ESP ablation between December 2014 and September 2022 was performed. Follow-up included telephone communication, letter questionnaire and outpatient presentation. Recurrence was based on typical symptoms.

Results: 115 patients aged 6-81 years (median age 36.3 years, 59.1% female; 26 pts < 18 years) were included. A typical history was present in all patients (100%), an ECG documentation of narrow complex tachycardia in 97 patients (84%). Patients were divided into three groups: Group 1 without DAVNP (n = 23), Group 2 with AH jump (n = 30) and Group 3 with AH jump and at least one AV nodal echo beat (n = 62). No permanent AV block was observed. During a median follow-up of 23.6 ± 22.7 months, symptom recurrence occurred in 7/115 patients (6.1%) with no significant difference between the groups (p = 0.73, log-rank test). Symptom recurrence occurred significantly more often in patients without (5/18 patients; 27%) as compared to patients with ECG documentation (2/97 patients; 2.1%; p = 0.025). No correlation between age and success rate was found (p > 0.1).

Conclusions: ESP ablation is effective and safe in patients with non-inducible AVNRT. Overall, recurrence of symptoms during long-term follow-up is low, even if no DAVNP is present. Tachycardia documentation before the EP study leads to a significantly lower recurrence rate following ESP ablation.

Keywords: atrioventricular nodal reentry tachycardia; dual atrioventricular nodal physiology; empirical slow pathway ablation; recurrence.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Kaplan–Meier analysis.

References

    1. Katritsis D.G., Zografos T., Siontis K.C., Giannopoulos G., Muthalaly R.G., Liu Q., Latchamsetty R., Varga Z., Deftereos S., Swerdlow C., et al. Endpoints for successful slow pathway catheter ablation in typical and atypical atrioventricular nodal re-entrant Tachycardia. JACC Clin. Electrophysiol. 2019;5:113–119. doi: 10.1016/j.jacep.2018.09.012. - DOI - PubMed
    1. Brugada J., Katritsis D.G., Arbelo E., Arribas F., Bax J.J., Blomström-Lundqvist C., Calkins H., Corrado D., Deftereos S.G., Diller G.P., et al. 2019 ESC Guidelines for the management of patients with supraventricular tachycardia. Eur. Heart J. 2020;41:683–685. doi: 10.1093/eurheartj/ehz467. - DOI
    1. Blomström-Lundqvist C., Scheinman M.M., Aliot E.M., Alpert J.S., Calkins H., Camm A.J., Campbell W.B., Haines D.E., Kuck K.H., Lerman B.B., et al. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias–executive summary. J. Am. Coll. Cardiol. 2003;42:1493–1531. doi: 10.1016/j.jacc.2003.08.013. - DOI - PubMed
    1. Wegner F.K., Silvano M., Bögeholz N., Leitz P.R., Frommeyer G., Dechering D.G., Zellerhoff S., Kochhäuser S., Lange P.S., Köbe J., et al. Slow pathway modification in patients presenting with only two consecutive AV nodal echo. J. Cardiol. 2017;69:471–475. doi: 10.1016/j.jjcc.2016.02.011. - DOI - PubMed
    1. Gerguri S., Jathanna N., Lin T., Müller P., Clasen L., Schmidt J., Kurt M., Shin D.I., Blockhaus C., Kelm M., et al. Clinical impact of “pure” empirical catheter ablation of slow-pathway in patients with non-ECG documented clinical on–of tachycardia. Eur. J. Med. Res. 2018;23:16. doi: 10.1186/s40001-018-0314-0. - DOI - PMC - PubMed

LinkOut - more resources