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Meta-Analysis
. 2023 Oct 29;23(1):820.
doi: 10.1186/s12903-023-03344-w.

The short- and long-term changes of upper airway and alar in nongrowing patients treated with Mini-Implant Assisted Rapid Palatal Expansion (MARPE): a systematic review and meta-analysis

Cuiyu Liu #  1 , Kaixin Wang #  1 , Chunmiao Jiang  1   2 , Yang Zhao  1   2 , Yiyan Zhang  1 , Qianwen Zhang  1 , Cunhui Fan  3   4 , Yang Liu  5   6
Affiliations
Meta-Analysis

The short- and long-term changes of upper airway and alar in nongrowing patients treated with Mini-Implant Assisted Rapid Palatal Expansion (MARPE): a systematic review and meta-analysis

Cuiyu Liu et al. BMC Oral Health. .

Abstract

Objective: This study aims to assess the short- and long-term changes in the upper airway and alar width after mini-implant -assisted rapid palatal expansion (MARPE) in nongrowing patients.

Methods: Five electronic databases (PubMed, Scopus, Embase, Web of Science, and Cochrane Library) were searched up to 2 August, 2023 based on the PICOS principles. The main outcomes were classified into three groups: 1) nasal cavity changes, 2) upper airway changes and 3) alar changes. The mean difference (MD) and 95% confidence intervals (CI) were used to assess these changes. Heterogeneity tests, subgroup analyses, sensitivity analyses, and publication bias were also analyzed.

Result: Overall, 22 articles were included for data analysis. Nasal cavity width (WMD: 2.05 mm; 95% CI: 1.10, 3.00) and nasal floor width (WMD: 2.13 mm; 95% CI: 1.16, 3.11) increased significantly. While palatopharyngeal volume (WMD: 0.29 cm3, 95% CI: -0.44, 1.01), glossopharyngeal volume (WMD: 0.30 cm3, 95% CI: -0.29, 0.89) and hypopharyngeal volume (WMD: -0.90 cm3; 95% CI: -1.86, 0.06) remained unchanged, nasal cavity volume (WMD: 1.24 cm3, 95% CI: 0.68, 1.81), nasopharyngeal volume (MD: 0.75 cm3, 95% CI: 0.44, 1.06), oropharyngeal volume (WMD: 0.61 cm3, 95% CI: 0.35, 0.87), and total volume of the upper airway (WMD: 1.67 cm3, 95% CI: 0.68, 2.66) increased significantly. Alar width (WMD: 1.47 mm; 95% CI: 0.40, 2.55) and alar base width (WMD: 1.54 mm; 95% CI: 1.21, 1.87) also increased.

Conclusion: MARPE can increase nasal cavity width, nasal cavity volume, nasopharyngeal volume and oropharyngeal volume for nongrowing patients, but has no significant effect on hypopharyngeal volume. In addition, the alar width also increased. However, the studies included in this meta-analysis were mainly retrospective, nonrandomized and small in number, so the findings should be interpreted with caution and high-quality RCTs need to be studied.

Keywords: Maxillary skeletal expansion; Mini-Implant Assisted Rapid Palatal Expansion (MARPE); Palatal expansion technique; Transverse maxillary deficiency; Upper airway volume.

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Conflict of interest statement

The authors declare no competing interests.

Figures

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Fig. 1
The PRISMA flow diagram
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References

    1. Brunelle JA, Bhat M, Lipton JA. Prevalence and distribution of selected occlusal characteristics in the US population, 1988–1991. J Dent Res. 1996;75 Spec No:706–713. doi: 10.1177/002203459607502S10. - DOI - PubMed
    1. Brunetto DP, Moschik CE, Dominguez-Mompell R, Jaria E, Sant'Anna EF, Moon W. Mini-implant assisted rapid palatal expansion (MARPE) effects on adult obstructive sleep apnea (OSA) and quality of life: a multi-center prospective controlled trial. Prog Orthod. 2022;23(1):3. doi: 10.1186/s40510-021-00397-x. - DOI - PMC - PubMed
    1. McNamara JA. Maxillary transverse deficiency. Am J Orthod Dentofacial Orthop. 2000;117(5):567–570. doi: 10.1016/S0889-5406(00)70202-2. - DOI - PubMed
    1. Baccetti T, Franchi L, Cameron CG, McNamara JA., Jr Treatment timing for rapid maxillary expansion. Angle Orthod. 2001;71(5):343–350. - PubMed
    1. Ahmida A, Mehta S, Amelemah E, Bashir R, Vich ML, Tadinada A, Allareddy V, Yadav S. Short-term and long-term effects of miniscrew-assisted and conventional rapid palatal expansion on the cranial and circummaxillary sutures. Am J Orthod Dentofac Orthop. 2023;163(4):E115–E126. doi: 10.1016/j.ajodo.2023.01.007. - DOI - PubMed

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