Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Oct 27:16:17562848231206991.
doi: 10.1177/17562848231206991. eCollection 2023.

A systematic review on diagnosis and treatment of gastrointestinal diseases by magnetically controlled capsule endoscopy and artificial intelligence

Xiaotong Wang  1 , Xiaoming Hu  1 , Yongxue Xu  1 , Jiahao Yong  1 , Xiang Li  1 , Kaixuan Zhang  1 , Tao Gan  2 , Jinlin Yang  3 , Nini Rao  4
Affiliations
Review

A systematic review on diagnosis and treatment of gastrointestinal diseases by magnetically controlled capsule endoscopy and artificial intelligence

Xiaotong Wang et al. Therap Adv Gastroenterol. .

Abstract

Background: Magnetically controlled capsule endoscopy (MCCE) is a non-invasive, painless, comfortable, and safe equipment to diagnose gastrointestinal diseases (GID), partially overcoming the shortcomings of conventional endoscopy and wireless capsule endoscopy (WCE). With advancements in technology, the main technical parameters of MCCE have continuously been improved, and MCCE has become more intelligent.

Objectives: The aim of this systematic review was to summarize the research progress of MCCE and artificial intelligence (AI) in the diagnosis and treatment of GID.

Data sources and methods: We conducted a systematic search of PubMed and EMBASE for published studies on GID detection of MCCE, physical factors related to MCCE imaging quality, the application of AI in aiding MCCE, and its additional functions. We synergistically reviewed the included studies, extracted relevant data, and made comparisons.

Results: MCCE was confirmed to have the same performance as conventional gastroscopy and WCE in detecting common GID, while it lacks research in detecting early gastric cancer (EGC). The body position and cleanliness of the gastrointestinal tract are the main factors affecting imaging quality. The applications of AI in screening intestinal diseases have been comprehensive, while in the detection of common gastric diseases such as ulcers, it has been developed. MCCE can perform some additional functions, such as observations of drug behavior in the stomach and drug damage to the gastric mucosa. Furthermore, it can be improved to perform a biopsy.

Conclusion: This comprehensive review showed that the MCCE technology has made great progress, but studies on GID detection and treatment by MCCE are in the primary stage. Further studies are required to confirm the performance of MCCE.

Keywords: detection; early gastric cancer; gastrointestinal diseases; magnetically controlled capsule endoscopy.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Figure 1.
Figure 1.
Flow diagram of the research method.
Figure 2.
Figure 2.
Gastric lesions examined by MCCE and the number of corresponding studies. MCCE, magnetically controlled capsule endoscopy.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Zhang X, Li M, Chen ST, et al.. Endoscopic screening in Asian countries is associated with reduced gastric cancer mortality: a meta-analysis and systematic review. Gastroenterology 2018; 155: 347–354.e9. - PubMed
    1. Carpi F, Galbiati S, Carpi A. Magnetic shells for gastrointestinal endoscopic capsules as a means to control their motion. Biomed Pharmacother 2006; 60: 370–374. - PubMed
    1. Hoang MC, Nguyen KT, Kim J, et al.. Automated bowel polyp detection based on actively controlled capsule endoscopy: feasibility study. Diagnostics 2021; 11: 1878–1893. - PMC - PubMed
    1. Beg S, Card T, Warburton S, et al.. Diagnosis of Barrett’s esophagus and esophageal varices using a magnetically assisted capsule endoscopy system. Gastrointest Endosc 2020; 91: 773–781.e1. - PubMed
    1. Xu YZ, Zhang W, Ye SL, et al.. The evaluation of the OMOM capsule endoscopy with similar pictures elimination mode. Clin Res Hepatol Gastroenterol 2014; 38: 757–762. - PubMed

LinkOut - more resources