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Review
. 2023 Sep 27;15(9):e46046.
doi: 10.7759/cureus.46046. eCollection 2023 Sep.

Advancements in Understanding Gastric Cancer: A Comprehensive Review

Khizer K Ansari  1 , Vasant Wagh  2 , Azeem I Saifi  3 , Iram Saifi  4 , Sharad Chaurasia  1
Affiliations
Review

Advancements in Understanding Gastric Cancer: A Comprehensive Review

Khizer K Ansari et al. Cureus. .

Abstract

As a complex and difficult condition, gastric cancer (GC) continues to have a big impact on the world's health. The goal of this review article is to give a thorough summary of the most recent developments and research discoveries in the field of stomach cancer. The review discusses a wide range of topics, such as the epidemiology and risk factors for GC, molecular insights into its pathogenesis, the use of biomarkers in diagnosis and prognosis, current and novel therapeutic approaches, and the intriguing potential of immunotherapy. In addition, procedures for surgery, therapy strategies, and imaging modalities for diagnosis and staging are examined. The paper emphasizes how crucial it is to comprehend the tumor microenvironment and how it affects the course of the disease. Overall, this review provides a comprehensive assessment of the current body of knowledge, highlights research gaps, and suggests future lines of inquiry to enhance the treatment of GC.

Keywords: advance treatment; ai; biomarkers; environmental and demographic risk factors; gastric cancer; prevention and screening.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. PRISMA methodology
PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses Image credits: Khizer K. Ansari
Figure 2
Figure 2. Various environmental and demographic risk factors
Image credits: Khizer K. Ansari
Figure 3
Figure 3. Various non-Invasive esting
Image credits: Khizer K. Ansari
See this image and copyright information in PMC

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