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. 2023 Sep;14(3):644-650.
doi: 10.1007/s13193-023-01730-y. Epub 2023 Mar 7.

Role of Selective Neck Dissection in Clinically Single Node Positive Disease in Oral Cavity Cancers

Rakesh Katna  1   2   3 , Bharat Bhosale  1   2   3 , Gaurav Naik  3 , Farhana Girkar  3 , Vijay Patil  4 , Ashay Karpe  3 , Nikhil Kalyani  1 ; Mumbai Oncology Group – Head, Neck
Affiliations

Role of Selective Neck Dissection in Clinically Single Node Positive Disease in Oral Cavity Cancers

Rakesh Katna et al. Indian J Surg Oncol. 2023 Sep.

Abstract

Management of the neck in oral cavity squamous carcinoma is debatable. There is controversy regarding role of SND in single node positive neck in oral SCC. The aim of this study was to determine the efficacy of selective neck dissection (SND) for cN1 neck in patients with oral cancer. A retrospective chart review of 266 oral cancer patients who were clinically single node positive from August 2013 to December 2019 was done. Patients having clinical or radiological cN1 disease undergoing SND were included. Two hundred sixty-six patients were analysed with 86% male predominance. Median age was 48 years. The commonest primary site was Bucco-alveolar complex (64%). Total of 319 SNDs were done in 266 patients. At median follow-up of 29 months, 29 patients (9%) had neck recurrence among which 4 patients had recurrence at level V, along with recurrence at other nodal levels. Three-year regional control was 86%, while DFS and OS were 66% and 68% respectively. For oral cancer with single clinically node positive neck (cN1), SND is an effective and oncological safe treatment. Outcomes are similar with modified neck dissection reported in the literature.

Keywords: Node positive; Oral cavity carcinoma; SND.

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Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flow chart for patient selection
Fig. 2
Fig. 2
Kaplan–Meier survival curve for regional control (whole cohort)
Fig. 3
Fig. 3
Kaplan–Meier survival curve for factors affecting regional control (univariate analysis)
See this image and copyright information in PMC

References

    1. GLOBOCAN. Estimated cancer incidence, mortality and prevalence worldwide in 2012: World Health Organization: International Agency for Research on Cancer, 2012
    1. Leemans CR, Tiwari R, Nauta JJ, van der Waal I, Snow GB. Regional lymph node involvement and its significance in the development of distant metastases in head and neck carcinoma. Cancer. 1993;71(2):452–6. doi: 10.1002/1097-0142(19930115)71:2<452::AID-CNCR2820710228>3.0.CO;2-B. - DOI - PubMed
    1. Fielding LP, Fenoglio-Preiser CM, Freedman LS. The future of prognostic factors in outcome prediction for patients with cancer. Cancer. 1992;70(9):2367–2377. doi: 10.1002/1097-0142(19921101)70:9<2367::AID-CNCR2820700927>3.0.CO;2-B. - DOI - PubMed
    1. Breau RL, Suen JY. Management of the N(0) neck. Otolaryngol Clin North Am. 1998;31(4):657–669. doi: 10.1016/S0030-6665(05)70078-5. - DOI - PubMed
    1. Santos AB, Cernea CR, Inoue M, Ferraz AR. Selective neck dissection for node- positive necks in patients with head and neck squamous cell carcinoma: a word of caution. Arch Otolaryngol Head Neck Surg. 2006;132(1):79–81. doi: 10.1001/archotol.132.1.79. - DOI - PubMed

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