Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 May 15;236(1):273-8.
doi: 10.1042/bj2360273.

Intralipid administration induces a lipoprotein lipase-like activity in the livers of starved adult rats

S Vilaró, M Reina, I Ramírez, M Llobera

Intralipid administration induces a lipoprotein lipase-like activity in the livers of starved adult rats

S Vilaró et al. Biochem J. .

Abstract

The administration of Intralipid to starved adult rats induces the appearance of lipoprotein lipase (LPL)-like activity in the liver, whereas the so-called hepatic triacylglycerol lipase is unaffected. This LPL-like activity is eluted by 1.5 M-NaCl from heparin-Sepharose columns. This partially purified fraction is inhibited by 1.0 M-NaCl (91%) and by 1.0 mg of protamine sulphate/ml (79%), whereas it is stimulated 69-fold by the presence of 8.0 micrograms of apolipoprotein C-II/ml and inhibited by anti-LPL antibodies. We conclude that Intralipid administration induces the appearance of LPL activity in livers of starved adult rats. Its possible origin is discussed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Lipid Res. 1969 May;10(3):341-4 - PubMed
    1. J Biol Chem. 1962 Nov;237:3423-9 - PubMed
    1. J Lipid Res. 1972 Jan;13(1):63-8 - PubMed
    1. J Biol Chem. 1973 Mar 25;248(6):1992-9 - PubMed
    1. FEBS Lett. 1975 Apr 1;52(2):191-4 - PubMed

Publication types