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. 2023 Jul-Aug;34(4):143-149.
doi: 10.1590/0103-6440202305405.

Efficacy of ClinproTMXT Varnish surrounding brackets on the enamel surface of white spot lesion

Ana Zilda Nazar Bergamo  1 , Lucas Portilho Miguel  1 , Renata Zoraida Rizental Delgado  1 , Regina Guenka Palma-Dibb  2 , Juliana Jendiroba Faraoni  2 , Patricia Gatón-Hernández  3 , Raquel Assed Bezerra da Silva  1 , Léa Assed Bezerra da Silva  1 , Paulo Nelson-Filho  1
Affiliations

Efficacy of ClinproTMXT Varnish surrounding brackets on the enamel surface of white spot lesion

Ana Zilda Nazar Bergamo et al. Braz Dent J. 2023 Jul-Aug.

Abstract
in English, Portuguese

Orthodontics patients usual develop demineralization and present cavity caries lesions after six months. Minimally invasive procedures have been the goal in modern dental practice. The aim of this study was to evaluate the effect of ClinproTMXT Varnish, on the enamel surface roughness and severity of white spot lesions. Twenty premolars were submitted to bond brackets and experimental induction of demineralization and randomly divided into 2 groups: GI - fluoride varnish (Colgate Duraphat®); GII - Ionomeric Sealant (ClinproTMXT Varnish). The treatment was applied around the brackets. The surface roughness of specimens was analyzed, before treatment and 12 weeks after treatment by laser confocal microscopy, and the severity of the white spot lesion was by laser fluorescence device. The data were analyzed by non-parametric Wilcoxon and Mann-Whitney Test, at 5% significance, roughness percentage reduction was performed. The severity of demineralization decreased in both, GI (p = 0.005) and GII (p = 0.019). Enamel superficial roughness levels decreased in GI and GII. As well as the roughness percentage, being more expressive in the ClinproTMXT Varnish group (85,09%). Colgate Duraphat® or Clinpro™ XT Varnish reduced the severity of the demineralization and decreased the superficial roughness on the enamel. The Clinpro™ XT Varnish was superior to superficial roughness on enamel.

Pacientes ortodônticos geralmente desenvolvem desmineralização e apresentam lesões de cárie após seis meses de tratamento. Procedimentos minimamente invasivos têm sido o objetivo na prática odontológica moderna. O objetivo deste estudo foi avaliar o efeito do ClinproTM XT selante ionomérico, ao redor do bráquete, com relação a rugosidade superficial do esmalte e a severidade da lesão induzida. Vinte pré-molares foram submetidos a colagem de bráquetes e indução experimental de desmineralização e divididos aleatoriamente em 2 grupos: GI - verniz fluoretado (Colgate Duraphat®); GII - Selante Ionomérico (ClinproTM XT). O tratamento foi aplicado ao redor dos bráquetes. A rugosidade da superfície dos espécimes foi analisada, antes do tratamento e 12 semanas após o tratamento por microscopia confocal a laser e severidade da lesão de mancha branca por dispositivo de fluorescência a laser. Os dados foram analisados pelo teste não paramétrico de Wilcoxon e Mann-Whitney, a 5% de significância. A taxa de redução da lesão foi calculada. A severidade da desmineralização diminuiu tanto no GI (p = 0,005) quanto no GII (p = 0,019). Os níveis de rugosidade superficial do esmalte diminuíram no GI e GII, assim como o percentual de rugosidade, sendo mais expressivo no grupo ClinproTMXT (85,09%). Colgate Duraphat® e Clinpro™ XT reduziram a severidade da desmineralização e diminuíram a rugosidade superficial do esmalte. O selante ionomérico Clinpro™ XT foi superior na redução percentual de rugosidade.

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Figures

Figure 1
Figure 1. Induction of White spot lesion.
Figure 2
Figure 2. Laser fluorescence evaluation - White spot lesion severity before and 12 weeks after a single application of Colgate Duraphat® and Clinpro™ XT Varnish. GI- Colgate Duraphat®; GII- Clinpro™ XT Varnish; T0- before treatment; T1- 12 weeks after treatment; SE- sound enamel; WS- white spot; * statistical significance; pGI=.005; pGII=.019.
Figure 3
Figure 3. Confocal laser microscopy representative images of superficial roughness obtained on sound enamel and white spot lesion before and 12 weeks after a single application of Colgate Duraphat® and Clinpro™ XT Varnish. A-sound enamel before treatment; B-sound enamel after treatment; C-white spot lesion before treatment; D-white spot lesion after treatment.
See this image and copyright information in PMC

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