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Case Reports
. 2023 Aug 31;40(4):2023-vol4.

[Case Report: MPO-ANCA Associated Vasculitis After Pfizer-BioNTech COVID-19 mRNA Vaccination]

[Article in Italian]
Fabio Mazza  1 , Angela Cicciarelli  1 , Filomena Rubino  1 , Martina Leopizzi  2 , Valeria Di Maio  2 , Bruna Cerbelli  2 , Paola Tatangelo  3 , Roberto Palumbo  3 , Ernesto Anselmo Cioffi  1 , Roberto Simonelli  4
Affiliations
  • PMID: 37910213
Case Reports

[Case Report: MPO-ANCA Associated Vasculitis After Pfizer-BioNTech COVID-19 mRNA Vaccination]

[Article in Italian]
Fabio Mazza et al. G Ital Nefrol. .

Abstract

We report a case of MPO-anti-neutrophil cytoplasmic antibody ANCA-associated vasculitis, with pulmonary-renal syndrome, after the mRNA booster third dose vaccine Pfizer BioNTech against COVID-19 in 71-year-old Caucasian man with no specific past medical history. A kidney biopsy diagnosed ANCA-associated pauci-immune crescentic glomerulonephritis. Renal function and constitutional symptoms have been partially improved with treatment with dialysis, intravenous rituximab and steroid pulse therapy. No disease following either infection or vaccination with fourth dose against COVID-19.

Keywords: ANCA vasculitis; SARS-CoV-2; booster dose; cytokine storm; mRNA vaccine.

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