Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;50(4):707-719.
doi: 10.1016/j.ogc.2023.08.005. Epub 2023 Sep 7.

Planned Oocyte Cryopreservation: A Review of Current Evidence on Outcomes, Safety and Risks

Bonnie B Song  1 , Molly M Quinn  2
Affiliations
Review

Planned Oocyte Cryopreservation: A Review of Current Evidence on Outcomes, Safety and Risks

Bonnie B Song et al. Obstet Gynecol Clin North Am. 2023 Dec.

Abstract

Although oocyte cryopreservation was initially used as a fertility preservation strategy for medical indications, it is now is increasingly used to circumvent age-related infertility. Outcomes following planned oocyte vitrification, also known as elective egg freezing, are limited. Current studies show higher success rates for individuals undergoing fertility preservation treatment under age 35. Additionally, while freezing 20 oocytes is optimal to achieve pregnancy, freezing at least 8-10 oocytes is recommended. While fertility is not guaranteed, current evidence demonstrates that planned oocyte vitrification is an overall safe, low risk method of fertility preservation to reduce the risk for age-related infertility.

Keywords: Elective egg freezing; Fertility preservation; Oocyte cryopreservation; Oocyte yield; Reproductive outcomes; Slow freezing; Vitrification.

PubMed Disclaimer

Conflict of interest statement

Disclosure The authors declare that they have no relevant or material financial interests that relate to the research described in this article.