Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
- PMID: 37919364
- PMCID: PMC10622517
- DOI: 10.1038/s41467-023-42960-6
Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
Abstract
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.
Conflict of interest statement
The authors declare no competing interests.
References
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- Hanahan D. Hallmarks of cancer: new dimensions. Cancer Discov. 2022;12:31–46. doi: 10.1158/2159-8290.CD-21-1059. - DOI - PubMed
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