TASL Practice Guidance on the Clinical Assessment and Management of Patients with Nonalcoholic Fatty Liver Disease
Affiliations
- 1 Department of Gastroenterology, Recep Tayyip Erdogan University, School of Medicine, Rize, Türkiye.
- 2 Department of Gastroenterology, Koc University School of Medicine, Istanbul, Türkiye.
- 3 Department of Gastroenterology, Health Sciences University, Umraniye Training and Research Hospital, Istanbul, Türkiye.
- 4 Department of Gastroenterology, Karadeniz Technical University School of Medicine, Trabzon, Türkiye.
- 5 Department of Oncology, Health Sciences University, Abdurrahman Yurtaslan Oncology Research and Training Hospital, Ankara, Türkiye.
- 6 Department of Gastroenterology, Ankara University School of Medicine, Ankara, Türkiye.
- 7 Department of Gastroenterology, Firat University School of Medicine, Elazig, Türkiye.
- 8 Department of Endocrinology, Ankara University School of Medicine, Ankara, Türkiye.
- 9 Department of Cardiology, Ankara University School of Medicine, Ankara, Türkiye.
- 10 Department of Nefrology, Ufuk University School of Medicine, Ankara, Türkiye.
- 11 Department of Gastroenterology, Ege University School of Medicine, Izmir, Türkiye.
- 12 Department of Radiology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 13 Department of Pathology, Marmara University School of Medicine, Istanbul, Türkiye.
- 14 Department of Pathology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Malatya, Türkiye.
- 15 Department of Pathology Gazi University School of Medicine, Ankara, Türkiye.
- 16 Department of Pathology, Ege University School of Medicine, Izmir, Türkiye.
- 17 Department of Pathology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 18 Department of Gastroenterology, Bahcesehir University School of Medicine, Istanbul, Türkiye.
- 19 Department of Gastroenterology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye.
- 20 Department of General Surgery, Ankara University School of Medicine, Ankara, Türkiye.
- 21 Department of Pathophysiology, Ankara University School of Medicine, Ankara, Türkiye.
- 22 Department of Pediatric Gastroenterology, Marmara University School of Medicine, Istanbul, Türkiye.
- 23 Department of Gastroenterology, Mersin University School of Medicine, Mersin, Türkiye.
- 24 Department of Gastroenterology, Akdeniz University School of Medicine, Antalya, Türkiye.
- 25 Department of Gastroenterology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 26 Department of Gastroenterology, Uludag University School of Medicine, Bursa, Türkiye.
- 27 Department of Gastroenterology, Health Sciences University, Ankara City Hospital, Ankara, Türkiye.
- 28 Department of Gastroenterology, Istanbul University Cerrahpasa School of Medicine, Türkiye.
- PMID: 37920782
- PMCID: PMC10588738
- DOI: 10.14744/hf.2023.2023.0011
TASL Practice Guidance on the Clinical Assessment and Management of Patients with Nonalcoholic Fatty Liver Disease
Authors
Affiliations
- 1 Department of Gastroenterology, Recep Tayyip Erdogan University, School of Medicine, Rize, Türkiye.
- 2 Department of Gastroenterology, Koc University School of Medicine, Istanbul, Türkiye.
- 3 Department of Gastroenterology, Health Sciences University, Umraniye Training and Research Hospital, Istanbul, Türkiye.
- 4 Department of Gastroenterology, Karadeniz Technical University School of Medicine, Trabzon, Türkiye.
- 5 Department of Oncology, Health Sciences University, Abdurrahman Yurtaslan Oncology Research and Training Hospital, Ankara, Türkiye.
- 6 Department of Gastroenterology, Ankara University School of Medicine, Ankara, Türkiye.
- 7 Department of Gastroenterology, Firat University School of Medicine, Elazig, Türkiye.
- 8 Department of Endocrinology, Ankara University School of Medicine, Ankara, Türkiye.
- 9 Department of Cardiology, Ankara University School of Medicine, Ankara, Türkiye.
- 10 Department of Nefrology, Ufuk University School of Medicine, Ankara, Türkiye.
- 11 Department of Gastroenterology, Ege University School of Medicine, Izmir, Türkiye.
- 12 Department of Radiology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 13 Department of Pathology, Marmara University School of Medicine, Istanbul, Türkiye.
- 14 Department of Pathology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Malatya, Türkiye.
- 15 Department of Pathology Gazi University School of Medicine, Ankara, Türkiye.
- 16 Department of Pathology, Ege University School of Medicine, Izmir, Türkiye.
- 17 Department of Pathology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 18 Department of Gastroenterology, Bahcesehir University School of Medicine, Istanbul, Türkiye.
- 19 Department of Gastroenterology, Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye.
- 20 Department of General Surgery, Ankara University School of Medicine, Ankara, Türkiye.
- 21 Department of Pathophysiology, Ankara University School of Medicine, Ankara, Türkiye.
- 22 Department of Pediatric Gastroenterology, Marmara University School of Medicine, Istanbul, Türkiye.
- 23 Department of Gastroenterology, Mersin University School of Medicine, Mersin, Türkiye.
- 24 Department of Gastroenterology, Akdeniz University School of Medicine, Antalya, Türkiye.
- 25 Department of Gastroenterology, Hacettepe University School of Medicine, Ankara, Türkiye.
- 26 Department of Gastroenterology, Uludag University School of Medicine, Bursa, Türkiye.
- 27 Department of Gastroenterology, Health Sciences University, Ankara City Hospital, Ankara, Türkiye.
- 28 Department of Gastroenterology, Istanbul University Cerrahpasa School of Medicine, Türkiye.
- PMID: 37920782
- PMCID: PMC10588738
- DOI: 10.14744/hf.2023.2023.0011
Abstract
Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease and is significantly associated with obesity, insulin resistance, type 2 diabetes mellitus, metabolic syndrome, and cardiovascular disease. NAFLD has become the most prevalent chronic liver disease in Western countries, and the proportion of NAFLD-related cirrhosis among patients on liver transplantation waiting lists has increased. In light of the accumulated data about NAFLD, and to provide a common approach with multi-disciplines dealing with the subject, it has become necessary to create new guidance for diagnosing and treating NAFLD. This guidance was prepared following an interdisciplinary study under the leadership of the Turkish Association for the Study of the Liver (TASL), Fatty Liver Special Interest Group. This new TASL Guidance is a practical application guide on NAFLD and was prepared to standardize the clinical approach to diagnosing and treating NAFLD patients. This guidance reflects many advances in the field of NAFLD. The proposals in this guidance are meant to aid decision-making in clinical practice. The guidance is primarily intended for gastroenterology, endocrinology, metabolism diseases, cardiology, internal medicine, pediatric specialists, and family medicine specialists.
Keywords: Nonalcoholic fatty liver disease; chronic hepatitis; cirrhosis; hepatosteatosis; nonalcoholic steatohepatitis; noninvasive diagnostic tests.
© Copyright 2023 by Hepatology Forum.
Conflict of interest statement
The authors have no conflict of interest to declare.
Figures

Figure 1
Diagnostic Scheme of Metabolic Disease-Associated…
Figure 1
Diagnostic Scheme of Metabolic Disease-Associated Fatty Liver Disease (MAFLD).

Figure 2
Scheme to Identify and Refer…
Figure 2
Scheme to Identify and Refer High-Risk Patients.

Figure 3
Current Endoscopic Bariatric and Metabolic…
Figure 3
Current Endoscopic Bariatric and Metabolic Treatments.
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