Scheduled intravenous opioids

Cathrine McKenzie^{1

2

3}, Yoanna Skrobik^{4

5}, John W Devlin^{6

7}

Affiliations

¹ National Institute of Health and Social Care Research (NIHR) Biomedical Research Centre, School of Medicine, Perioperative and Critical Care Theme and NIHR Applied Research Collaborative (ARC), University of Southampton, Wessex, Southampton, UK.
² Pharmacy and Critical Care, University Hospital, Southampton NHS Foundation Trust, Southampton, UK.
³ Institute of Pharmaceutical Sciences, School of Cancer and Pharmacy, King's College London, London, UK.
⁴ Department of Medicine, McGill University, Montreal, QC, Canada.
⁵ Department of Medicine, Cambridge University, Cambridge, UK.
⁶ School of Pharmacy and Pharmaceutical Sciences, Bouve College of Health Sciences, Northeastern University, Boston, MA, USA. j.devlin@neu.edu.
⁷ Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA. j.devlin@neu.edu.

PMID: 37922011
PMCID: PMC10709215
DOI: 10.1007/s00134-023-07254-x

Scheduled intravenous opioids

Cathrine McKenzie et al. Intensive Care Med. 2023 Dec.

. 2023 Dec;49(12):1541-1543.

doi: 10.1007/s00134-023-07254-x. Epub 2023 Nov 3.

Authors

Cathrine McKenzie^{1

2

3}, Yoanna Skrobik^{4

5}, John W Devlin^{6

7}

Affiliations

¹ National Institute of Health and Social Care Research (NIHR) Biomedical Research Centre, School of Medicine, Perioperative and Critical Care Theme and NIHR Applied Research Collaborative (ARC), University of Southampton, Wessex, Southampton, UK.
² Pharmacy and Critical Care, University Hospital, Southampton NHS Foundation Trust, Southampton, UK.
³ Institute of Pharmaceutical Sciences, School of Cancer and Pharmacy, King's College London, London, UK.
⁴ Department of Medicine, McGill University, Montreal, QC, Canada.
⁵ Department of Medicine, Cambridge University, Cambridge, UK.
⁶ School of Pharmacy and Pharmaceutical Sciences, Bouve College of Health Sciences, Northeastern University, Boston, MA, USA. j.devlin@neu.edu.
⁷ Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA. j.devlin@neu.edu.

PMID: 37922011
PMCID: PMC10709215
DOI: 10.1007/s00134-023-07254-x

No abstract available

PubMed Disclaimer

Conflict of interest statement

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Cited by

Neurotoxicity of sedative drugs: a matter of concern in adults?
Landoni G, Kotani Y, Lomivorotov V. Landoni G, et al. Intensive Care Med. 2025 Jul 24. doi: 10.1007/s00134-025-08030-9. Online ahead of print. Intensive Care Med. 2025. PMID: 40705075 No abstract available.

References

1. Devlin JW, Skrobik Y, Gelinas C, Pandharipande P, et al. Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the intensive care unit. Crit Care Med. 2018;46(9):e825–e873. doi: 10.1097/CCM.0000000000003299. - DOI - PubMed
1. Casey E, Lane Aoife L, Kuriakose D, et al. Bolus remifentanil for chest drain removal in the ICU: a randomized double-blind comparison of three modes of analgesia in post-cardiac surgical patients. Intensive Care Med. 2010;36(8):1380–1385. doi: 10.1007/s00134-010-1836-2. - DOI - PubMed
1. Barr J, Fraser GL, Puntillo K, et al. Clinical practice guidelines for the management of pain, agitation and delirium in adult ICU patients. Crit Care Med. 2013;41:263–306. doi: 10.1097/CCM.0b013e3182783b72. - DOI - PubMed
1. Bolesta S, Burry L, Perreault MM, et al. International analgesia and sedation weaning and withdrawal practices in critically ill adults: the adult iatrogenic withdrawal study in the ICU. Crit Care Med. 2023;51:1502–1514. doi: 10.1097/CCM.0000000000005951. - DOI - PubMed
1. Eadie R, McKenzie CA, Hadfield D, et al. Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study. Int J Clin Pharm. 2023;45:1167–1175. doi: 10.1007/s11096-023-01614-9. - DOI - PMC - PubMed

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Scheduled intravenous opioids

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