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. 2024 Mar;40(3):415-417.
doi: 10.1007/s12264-023-01148-0. Epub 2023 Nov 5.

Prefrontocortical Astrocytes Regulate Dominance Hierarchy in Male Mice

Yong Tang  1   2 , Hai-Yan Yin  3 , Peter Illes  4   5
Affiliations

Prefrontocortical Astrocytes Regulate Dominance Hierarchy in Male Mice

Yong Tang et al. Neurosci Bull. 2024 Mar.
No abstract available

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Conflict of interest statement

The authors declare that they have no competing interest.

Figures

Fig. 1
Fig. 1
Hypothetical astrocyte-dependent and neuronally executed mechanisms underlying the establishment of behavioral dominance in the tube test. For further explanation see the text. [Ca2+]i intracellular Ca2+ concentration; Glu Glutamate; ATP Adenosine 5’-triphosphate; P2X2 P2X2 receptor; P2Y1 P2Y1 receptor; GABAA γ-aminobutyrate receptor; mGlu Metabotropic glutamate receptor; iGlu Ionotropic glutamate receptor, upward arrow, stimulation; downward arrow, inhibition
See this image and copyright information in PMC

References

    1. Fan Z, Zhu H, Zhou T, Wang S, Wu Y, Hu H. Using the tube test to measure social hierarchy in mice. Nat Protoc. 2019;14:819–831. doi: 10.1038/s41596-018-0116-4. - DOI - PubMed
    1. Wang F, Zhu J, Zhu H, Zhang Q, Lin Z, Hu H. Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science. 2011;334:693–697. doi: 10.1126/science.1209951. - DOI - PubMed
    1. Wang F, Kessels HW, Hu H. The mouse that roared: Neural mechanisms of social hierarchy. Trends Neurosci. 2014;37:674–682. doi: 10.1016/j.tins.2014.07.005. - DOI - PubMed
    1. Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, et al. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature. 2011;477:171–178. doi: 10.1038/nature10360. - DOI - PMC - PubMed
    1. Noh K, Cho WH, Lee BH, Kim DW, Kim YS, Park K, et al. Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance. Nat Neurosci. 2023;26:1541–1554. doi: 10.1038/s41593-023-01406-4. - DOI - PubMed

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